Green synthesis of graphene nanosheets and their in vitro cytotoxicity against human prostate cancer (DU 145) cell lines

被引：28

作者：

Zhu, Xin ^{[1
]}

Xu, Xiaolin ^{[1
]}

Liu, Feng ^{[1
]}

Jin, Jizhong ^{[1
]}

Liu, Lintao ^{[1
]}

Zhi, Yi ^{[2
]}

Chen, Zhi-wen ^{[2
]}

Zhou, Zhan-song ^{[2
]}

Yu, Jianjun ^{[1
]}

机构：

[1] Shanghai Fengxian Dist Cent Hosp, Dept Urol, Shanghai, Peoples R China

[2] Third Mil Med Univ, Southwest Hosp, Urol Inst People Liberat Army, Chongqing, Peoples R China

来源：

NANOMATERIALS AND NANOTECHNOLOGY | 2017年 / 7卷

关键词：

Citrullus colocynthis; cytotoxicity; oxidized polyphenols; RGO; OXIDE NANOSHEETS; ETHANOL OXIDATION; NANOPARTICLES; TRANSPARENT; REDUCTION; GRAPHITE; EXFOLIATION; DECORATION; ELECTRODES; EXTRACT;

D O I：

10.1177/1847980417702794

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

A simple and green approach for the synthesis of polyphenol-functionalized reduced graphene oxide nanosheets is demonstrated, using leaf extract of Citrullus colocynthis as a deoxygenating agent. The C. colocynthis polyphenols also play a significant role as a stabilizing agent, preventing agglomeration of reduced graphene oxide nanosheets. Cytotoxicity tests showed that the both graphene oxide and Citrullus colocynthis polyphenol-stabilized reduced graphene oxide were toxic to DU145 cells; the cytotoxicity was dose dependent. Hence, C. colocynthis-mediated reduced graphene oxide may be an ideal anticancer material for biological study applications.

引用

页数：7

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