Methyldopa electrochemical sensor based on a glassy carbon electrode modified with Cu/TiO2 nanocomposite

被引：106
作者：
Tajik, Somayeh [1 ]
Beitollahi, Hadi [2 ]
Biparva, Pourya [3 ]
机构：
[1] Bam Univ Med Sci, Bam, Iran
[2] Grad Univ Adv Technol, Inst Sci & High Technol & Environm Sci, Environm Dept, Kerman, Iran
[3] Sari Agr Sci & Nat Resources Univ, Dept Basic Sci, Sari, Iran
来源：
JOURNAL OF THE SERBIAN CHEMICAL SOCIETY | 2018年 / 83卷 / 7-8期
关键词：
methyldopa; Cu/TiO2; nanocomposite; graphite screen printed electrode; voltammetry; NANOTUBE PASTE ELECTRODE; VOLTAMMETRIC DETERMINATION; ASCORBIC-ACID; PHARMACEUTICAL FORMULATIONS; ALPHA-METHYLDOPA; REAL SAMPLES; HUMAN SERUM; FOLIC-ACID; 1ST REPORT; THIN-FILM;
D O I：
10.2298/JSC170930024T
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A Cu/TiO2 nanocomposite modified glassy carbon electrode (Cu//TiO2/GCE) was fabricated to detect methyldopa by cyclic voltammetry (CV) and different pulse voltammetry (DPV) methods. Compared with bare GCE, the Cu/TiO2/GCE exhibited excellent electrochemical activity for the oxidation of methyldopa. Using DPV technique, the calibration curves for methyldopa were found linear in the concentration range of 0.5-800.0 mu M and the detection limit (S/N = 3) was calculated to be 0.23 mu M. Additionally, the prepared electrochemical sensor of Cu/TiO2/GCE demonstrated a practical feasibility in methyldopa tablets and in urine samples analysis.
引用
收藏
页码：863 / 874
页数：12
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