Organic impurity profiling of 3,4-methylenedioxymethamphetamine (MDMA) tablets seized in the Netherlands

被引：28

作者：

van Deursen, M. M. ^{[1
]}

Lock, E. R. A. ^{[1
]}

Meer, A. J. Poortman-van der ^{[1
]}

机构：

[1] Netherlands Forens Inst, NL-2490 AA The Hague, Netherlands

来源：

SCIENCE & JUSTICE | 2006年 / 46卷 / 03期

关键词：

MDMA; profiling; comparison; gas chromatography mass spectrometry;

D O I：

10.1016/S1355-0306(06)71588-X

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

In this study, a new method was developed for the impurity profiling of illicit MDMA tablets. The extraction efficiency, linearity, repeatability and reproducibility of the method were evaluated. Eighty two MDMA tablets coming from presumed unrelated large seizures in 2004 (n > 500 tablets) were analyzed by gas chromatography mass spectrometry (GC-MS) in order to assess the discrimination power of the method. The latter was found to be practical, robust, relatively easy to perform, highly discriminative and yielding good chromatography. In addition, some new impurities were detected and identified. Their chemical structures and mass spectra are reported.

引用

页码：135 / 152

页数：18

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