Assessment of severity of leukoaraiosis: a diffusional kurtosis imaging study

被引：7

作者：

Xu, Shuhui ^{[1
]}

Ye, Deqiu ^{[1
]}

Lian, Tao ^{[1
]}

Cai, Jianzhong ^{[2
]}

Xiao, Zebin ^{[3
]}

Huang, Yongchu ^{[1
]}

Chen, Xiangrong ^{[1
]}

Zhang, Zhongping ^{[4
]}

机构：

[1] Fujian Med Univ, Quanzhou Hosp 1, Dept Radiol, Quanzhou 362000, Fujian, Peoples R China

[2] Shishi City Hosp, Dept Radiol, Quanzhou 362700, Fujian, Peoples R China

[3] Fujian Med Univ, Affiliated Hosp 1, Dept Radiol, Fuzhou 350005, Fujian, Peoples R China

[4] GE Healthcare China, Guangzhou 510623, Guangdong, Peoples R China

来源：

CLINICAL IMAGING | 2016年 / 40卷 / 04期

关键词：

Diffusion; Kurtosis; DKI; Non-Gaussians; Leukoaraiosis; GAUSSIAN WATER DIFFUSION; WHITE-MATTER LESIONS; TENSOR; ABNORMALITIES; FEATURES; TISSUES; COHORT; LADIS;

D O I：

10.1016/j.clinimag.2016.02.018

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Objective: The objective was to investigate the capabilities of diffusional kurtosis imaging (DKI) in detection of age-related white matter (WM) changes in elderly patients with leukoaraiosis. Material and methods: Fractional anisotropy (FA), kurtosis, and diffusion parameters in the frontal lobe and parietal lobe were compared between 14 patients at Fazekas scale 0 and 1, and 15 patients at Fazekas scale 2 and 3. Results: FA and DIU parameters were significantly altered in the ischemic lesions vs normal regions of WM in the severe patients. Conclusion: DKI can provide sensitive imaging biomarkers for assessing the severity of leukoaraiosis in reference to Fazekas score. (C) 2016 Elsevier Inc. All rights reserved.

引用

页码：732 / 738

页数：7

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