Synthesis of hollow structural hydroxyapatite with different morphologies using calcium carbonate as hard template

被引：36

作者：

Xia, Xu ^{[1
]}

Chen, Jiwei ^{[1
]}

Shen, Juan ^{[1
,2
]}

Huang, Di ^{[3
]}

Duan, Peizhen ^{[1
]}

Zou, Guohong ^{[1
]}

机构：

[1] Southwest Univ Sci & Technol, Sch Mat Sci & Engn, Mianyang 621010, Peoples R China

[2] Southwest Univ Sci & Technol, State Key Lab Cultivat Base Nonmetal Composites &, Mianyang 621010, Peoples R China

[3] Taiyuan Univ Technol, Coll Mech, Taiyuan 030024, Shanxi, Peoples R China

来源：

ADVANCED POWDER TECHNOLOGY | 2018年 / 29卷 / 07期

基金：

中国国家自然科学基金;

关键词：

Calcium carbonate; Conversion; Hydroxyapatite; Hydrothermal treatment; Formation mechanism; HYDROTHERMAL SYNTHESIS; RAPID SYNTHESIS; MICROSPHERES; COPRECIPITATION; TRANSFORMATION; NANOPARTICLES; RELEASE; GROWTH; ROUTE; FABRICATION;

D O I：

10.1016/j.apt.2018.03.021

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

Hydroxyapatite (HAp) with hollow structure was successfully synthesized by hydrothermal process of asprepared calcium carbonate used as a hard template and calcium sources in a diammonium phosphate solution. Calcium carbonate was fabricated by precipitation, which possessed different morphologies such as balls, rods and blocks through regulating the amount of citric acid. The synthesized powders were characterized by X-ray diffraction (XRD), Fourier transform infrared spectrograph (FT-IR), field-emission scanning electron microscope (FESEM) and high-resolution transmission electron microscopy (HRTEM) and nitrogen adsorption-desorption. Results indicated that different morphologies calcium carbonate could convert to hollow structural HAp with the higher BET surface area and the mesopores. Hydrothermal temperature and hydrothermal time play a slight role on transition percentage. As hydrothermal temperature and hydrothermal time increased, the conversion rate of calcium carbonate to hydroxyapatite increased. The possible formation mechanism of hydroxyapatite was preliminarily investigated. The resultants of HAp are interesting materials for drug delivery and sustained-release. (C) 2018 The Society of Powder Technology Japan. Published by Elsevier B.V. and The Society of Powder Technology Japan. All rights reserved.

引用

页码：1562 / 1570

页数：9

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