Dose coefficients of percentile-specific computational phantoms for photon external exposures

被引:5
作者
Yeom, Yeon Soo [1 ]
Han, Haegin [2 ]
Choi, Chansoo [2 ]
Shin, Bangho [2 ]
Kim, Chan Hyeong [2 ]
Lee, Choonsik [1 ]
机构
[1] NCI, Div Canc Epidemiol & Genet, NIH, Rockville, MD 20850 USA
[2] Hanyang Univ, Dept Nucl Engn, 222 Wangsimni Ro, Seoul 04763, South Korea
基金
美国国家卫生研究院; 新加坡国家研究基金会;
关键词
Body size; Computational phantom; Photon; Dose coefficient; Monte Carlo; LIBRARY; CONSTRUCTION;
D O I
10.1007/s00411-019-00818-w
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The use of dose coefficients (DCs) based on the reference phantoms recommended by the International Commission on Radiological Protection (ICRP) with a fixed body size may produce errors to the estimated organ/tissue doses to be used, for example, for epidemiologic studies depending on the body size of cohort members. A set of percentile-specific computational phantoms that represent 10th, 50th, and 90th percentile standing heights and body masses in adult male and female Caucasian populations were recently developed by modifying the mesh-type ICRP reference computational phantoms (MRCPs). In the present study, these percentile-specific phantoms were used to calculate a comprehensive dataset of body-size-dependent DCs for photon external exposures by performing Monte Carlo dose calculations with the Geant4 code. The dataset includes the DCs of absorbed doses for 29 individual organs/tissues from 0.01 to 10(4) MeV photon energy, in the antero-posterior, postero-anterior, right lateral, left lateral, rotational, and isotropic geometries. The body-size-dependent DCs were compared with the DCs of the MRCPs in the reference body size, showing that the DCs of the MRCPs are generally similar to those of the 50th percentile standing height and body mass phantoms over the entire photon energy region except for low energies (<= 0.03 MeV); the differences are mostly less than 10%. In contrast, there are significant differences in the DCs between the MRCPs and the 10th and 90th percentile standing height and body mass phantoms (i.e., H10M10 and H90M90). At energies of less than about 10 MeV, the MRCPs tended to under- and over-estimate the organ/tissue doses of the H10M10 and H90M90 phantoms, respectively. This tendency was revised at higher energies. The DCs of the percentile-specific phantoms were also compared with the previously published values of another phantom sets with similar body sizes, showing significant differences particularly at energies below about 0.1 MeV, which is mainly due to the different locations and depths of organs/tissues between the different phantom libraries. The DCs established in the present study should be useful to improve the dosimetric accuracy in the reconstructions of organ/tissue doses for individuals in risk assessment for epidemiologic investigations taking body sizes into account.
引用
收藏
页码:151 / 160
页数:10
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