Synthesis of hydronaphthalenes through coupling of enyne-carbonyl compounds that contain pendant alkane groups with Fischer carbene complexes

被引：4

作者：

Patti, Rajesh Kumar ^{[1
]}

Duan, Shaofeng ^{[1
]}

Camacho-Davila, Alejandro ^{[1
]}

Waynant, Kris ^{[1
]}

Dunn, Kenneth A. ^{[1
]}

Herndon, James W. ^{[1
]}

机构：

[1] New Mexico State Univ, Dept Chem & Biochem, Las Cruces, NM 88003 USA

来源：

TETRAHEDRON LETTERS | 2010年 / 51卷 / 28期

关键词：

DIELS-ALDER REACTION; FURAN-DIENE; CYCLOADDITION CHEMISTRY; DERIVATIVES; ALDEHYDES; SYSTEMS; KETONES;

D O I：

10.1016/j.tetlet.2010.05.049

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The coupling of enyne-carbonyl compounds that contain pendant alkene groups with Fischer carbene complexes to afford furans that contain pendant alkene groups is described. Subsequent intramolecular Diels-Alder reactions are effective in selected cases, resulting in hydronaphthalene systems after dehydration. Although the Diels-Alder event is thermodynamically unfavorable, the overall transformation of alkene-furans to dihydronaphthalenes is a favorable process. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：3682 / 3684

页数：3