Meta-analysis of randomized clinical trials of finasteride

被引：13

作者：

Roehrborn, CG ^{[1
]}

机构：

[1] Univ Texas, SW Med Ctr, Dept Urol, Urol Sect,Vet Adm N Texas Hlth Care Syst, Dallas, TX 75232 USA

来源：

UROLOGY | 1998年 / 51卷 / 4A期

关键词：

D O I：

10.1016/S0090-4295(98)00055-7

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

A meta-analysis was recently published based on six randomized clinical trials of at least one year duration involving finasteride 5 mg and placebo in the treatment of men with clinical benign prostatic hyperplasia (BPH). In a pooled analysis, mean improvement in symptoms and urinary flow rate with finasteride were found to increase with increasing prostate size. This article reviews the previous publication of this meta-analysis, which indicated prostate volume is a key predictor of outcomes with finasteride treatment and suggested that finasteride is most effective in men with large prostates. (C) 1998, Elsevier Science Inc. All rights reserved.

引用

页码：46 / 49

页数：4

共 23 条

[1] CAN FINASTERIDE REVERSE THE PROGRESS OF BENIGN PROSTATIC HYPERPLASIA - A 2-YEAR PLACEBO-CONTROLLED STUDY [J].

ANDERSEN, JT ;

EKMAN, P ;

WOLF, H ;

BEISLAND, HO ;

JOHANSSON, JE ;

KONTTURI, M ;

LEHTONEN, T ;

TVETER, K ;

BODKER, A ;

VEDEL, O ;

NORDLING, J ;

POULSEN, AL ;

SCHOU, J ;

HVIDT, V ;

HANSEN, JB ;

MEYHOFF, HH ;

ELDRUP, J ;

HARTWELL, D ;

COLSTRUP, H ;

LYNGDORF, P ;

NIELSEN, AH ;

LARSEN, E ;

WALTER, S ;

LARSEN, EH ;

THYBO, E ;

MOMMSEN, S ;

BROK, KE ;

PALM, L ;

GENSTER, H ;

ANDERSEN, M ;

KAUPPINEN, P ;

RAUVALA, M ;

HAKKINEN, J ;

TAMMELA, T ;

TAINIO, H ;

HYNNINEN, O ;

TIITINEN, J ;

LEHTORANTA, K ;

ALAOPAS, M ;

PERTTILA, I ;

PETAS, A ;

RINTALA, E ;

SALMINEN, R ;

JUUSELA, H ;

HANSSON, E ;

VONWENDT, R ;

TUHKANEN, K ;

TALJA, M ;

NURMI, M ;

PUNTALA, P .

UROLOGY, 1995, 46 (05) :631-637

[2]

BARRETT D, 1997, J UROLOGY, V157, P518

[3]

Bonilla J, 1997, PROSTATE, V31, P98, DOI 10.1002/(SICI)1097-0045(19970501)31:2<98::AID-PROS4>3.0.CO

[4]

2-D

[5] PARAMETERS OF PROSTATE VOLUME AND SHAPE IN A COMMUNITY-BASED POPULATION OF MEN 55 TO 74 YEARS OLD [J].

BOSCH, JLHR ;

HOP, WCJ ;

NIEMER, AQHJ ;

BANGMA, CH ;

KIRKELS, WJ ;

SCHRODER, FH .

JOURNAL OF UROLOGY, 1994, 152 (05) :1501-1505

[6] Prostate volume predicts outcome of treatment of benign prostatic hyperplasia with finasteride: Meta-analysis of randomized clinical trials [J].

Boyle, P ;

Gould, AL ;

Roehrborn, CG .

UROLOGY, 1996, 48 (03) :398-405

[7] TRANSURETHRAL MICROWAVE THERMOTHERAPY (TUMT) IN BENIGN PROSTATIC HYPERPLASIA - PLACEBO VERSUS TUMT [J].

DELAROSETTE, JJMCH ;

DEWILDT, MJAM ;

ALIVIZATOS, G ;

FROELING, FMJA ;

DEBRUYNE, FMJ .

UROLOGY, 1994, 44 (01) :58-63

[8] A 12-month study of the placebo effect in transurethral microwave thermotherapy [J].

DeWildt, MJAM ;

Hubregtse, M ;

Ogden, C ;

Carter, SS ;

Debruyne, FMJ ;

DeLaRosette, JJMCH .

BRITISH JOURNAL OF UROLOGY, 1996, 77 (02) :221-227

[9] HIGH PREVALENCE OF BENIGN PROSTATIC HYPERTROPHY IN THE COMMUNITY [J].

GARRAWAY, WM ;

COLLINS, GN ;

LEE, RJ .

LANCET, 1991, 338 (8765) :469-471

[10] NATURAL-HISTORY OF PROSTATISM - RELATIONSHIP AMONG SYMPTOMS, PROSTATE VOLUME AND PEAK URINARY FLOW-RATE [J].

GIRMAN, CJ ;

JACOBSEN, SJ ;

GUESS, HA ;

OESTERLING, JE ;

CHUTE, CG ;

PANSER, LA ;

LIEBER, MM .

JOURNAL OF UROLOGY, 1995, 153 (05) :1510-1515

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