Recalibrating the risks and benefits of lithium therapy

被引：15
作者：
Berk, Michael [1 ,5 ]
Cowdery, Stephanie [2 ,6 ]
Williams, Lana [2 ,6 ]
Malhi, Gin S. [3 ,4 ,7 ]
机构：
[1] Deakin Univ, Psychiat, Geelong, Vic, Australia
[2] Deakin Univ, Kitchener House, Geelong, Vic 3220, Australia
[3] Univ Sydney, Dept Psychiat, Sydney, NSW, Australia
[4] CADE Clin Royal North Shore Hosp, St Leonards, NSW, Australia
[5] Deakin Univ, Sch Med, Fac Hlth, Geelong, Vic, Australia
[6] Deakin Univ, Sch Med, Fac Hlth, IMPACT Strateg Res Ctr, Geelong, Vic, Australia
[7] Univ Sydney, CADE Clin, North Shore Hosp, Sydney, NSW, Australia
来源：
BRITISH JOURNAL OF PSYCHIATRY | 2017年 / 211卷 / 01期
基金：
澳大利亚国家健康与医学研究理事会;
关键词：
BIPOLAR DISORDER; CANCER; COHORT;
D O I：
10.1192/bjp.bp.116.193789
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
Recent data might subtly recalibrate the risk/benefit ratio of lithium, the prototypical mood stabiliser for bipolar disorder. There are hints that lithium might be associated with a reduction in dementia risk and as noted in this Journal, a surprising reduction in the risk of cancer.
引用
收藏
页码：1 / 2
页数：2
相关论文
共 11 条
[1]   Lithium in the prevention of suicide in mood disorders: updated systematic review and meta-analysis [J].
Cipriani, Andrea ;
Hawton, Keith ;
Stockton, Sarah ;
Geddes, John R. .
BMJ-BRITISH MEDICAL JOURNAL, 2013, 346
[2]   Lithium vs. valproate vs. olanzapine vs. quetiapine as maintenance monotherapy for bipolar disorder: a population-based UK cohort study using electronic health records [J].
Hayes, Joseph F. ;
Marston, Louise ;
Walters, Kate ;
Geddes, John R. ;
King, Michael ;
Osborn, David P. J. .
WORLD PSYCHIATRY, 2016, 15 (01) :53-58
[3]   Use of lithium and cancer risk in patients with bipolar disorder: population-based cohort study [J].
Huang, Ru-Yu ;
Hsieh, Kun-Pin ;
Huang, Wan-Wen ;
Yang, Yi-Hsin .
BRITISH JOURNAL OF PSYCHIATRY, 2016, 209 (05) :395-401
[4]   Lithium Treatment and Risk of Dementia [J].
Kessing, Lars Vedel ;
Sondergard, Lars ;
Forman, Julie Lyng ;
Andersen, Per Kragh .
ARCHIVES OF GENERAL PSYCHIATRY, 2008, 65 (11) :1331-1335
[5]   Using lithium as a neuroprotective agent in patients with cancer [J].
Khasraw, Mustafa ;
Ashley, David ;
Wheeler, Greg ;
Berk, Michael .
BMC MEDICINE, 2012, 10
[6]   Potential Mechanisms of Action of Lithium in Bipolar Disorder Current Understanding [J].
Malhi, Gin S. ;
Tanious, Michelle ;
Das, Pritha ;
Coulston, Carissa M. ;
Berk, Michael .
CNS DRUGS, 2013, 27 (02) :135-153
[7]   Lithium treatment and cancer incidence in bipolar disorder [J].
Martinsson, Lina ;
Westman, Jeanette ;
Hallgren, Jonas ;
Osby, Urban ;
Backlund, Lena .
BIPOLAR DISORDERS, 2016, 18 (01) :33-40
[8]   The Putative Use of Lithium in Alzheimer's Disease [J].
Morris, Gerwyn ;
Berk, Michael .
CURRENT ALZHEIMER RESEARCH, 2016, 13 (08) :853-861
[9]   Long-term use of lithium and risk of colorectal adenocarcinoma: a nationwide case-control study [J].
Pottegard, Anton ;
Ennis, Zandra Nymand ;
Hallas, Jesper ;
Jensen, Boye L. ;
Madsen, Kirsten ;
Friis, Soren .
BRITISH JOURNAL OF CANCER, 2016, 114 (05) :571-575
[10]   Long-Term Lithium Use and Risk of Renal and Upper Urinary Tract Cancers [J].
Pottegard, Anton ;
Hallas, Jesper ;
Jensen, Boye L. ;
Madsen, Kirsten ;
Friis, Soren .
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2016, 27 (01) :249-255
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