Extranodal Marginal Zone Lymphoma From Ocular Adnexae With Subcutaneous Involvement

被引:2
作者
Beltran, Brady E. [1 ]
Castillo, Jorge J. [2 ]
Quinones, Pilar [3 ]
Morales, Domingo [3 ]
Paredes, Antonio [4 ]
Nieto, Giuliana [4 ]
Miranda, Roberto N. [5 ]
Torres-Cabala, Carlos A. [6 ,7 ]
机构
[1] Edgardo Rebagliati Martins Hosp, Dept Radiotherapy & Oncol, Lima, Peru
[2] Brown Univ, Rhode Isl Hosp, Div Hematol & Oncol, Warren Alpert Med Sch, Providence, RI 02903 USA
[3] Edgardo Rebagliati Martins Hosp, Dept Pathol, Lima, Peru
[4] Edgardo Rebagliati Martins Hosp, Div Dermatol, Lima, Peru
[5] Univ Texas MD Anderson Canc Ctr, Dept Hematopathol, Houston, TX 77030 USA
[6] Univ Texas MD Anderson Canc Ctr, Dept Pathol, Houston, TX 77030 USA
[7] Univ Texas MD Anderson Canc Ctr, Dept Dermatol, Houston, TX 77030 USA
关键词
MALT; lymphoma; extranodal; subcutaneous; ocular adnexa; B-CELL LYMPHOMA; TISSUE LYMPHOMA; LARGE COHORT; MALT;
D O I
10.1097/DAD.0000000000000050
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Extranodal marginal zone lymphoma (MZL) of mucosa-associated lymphoid tissue usually originates from cutaneous or mucosal surfaces. A rare site of involvement is the subcutaneous tissue of any location. Here, we describe a 58-year-old man who presented with bilateral extranodal MZL of mucosa-associated lymphoid tissue from ocular adnexae that involved subcutaneous tissue and subsequently extended to multiple anatomical locations in the head and neck, upper back, and arm. The neoplastic cells expressed B-cell markers, and the plasma cells expressed IgG4. The unusual pattern of infiltration of this extranodal MZL and the possible significance of IgG4 expression in this case are discussed.
引用
收藏
页码:E189 / E193
页数:5
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