Efficacy and Safety of Anti-D for Immune Thrombocytopenic Purpura in Children

被引:2
作者
Naithani, Rahul [1 ]
Kumar, Rajat [1 ]
Mahapatra, M. [1 ]
Tyagi, Seema [1 ]
Mishra, Pravas [1 ]
机构
[1] All India Inst Med Sci, Dept Hematol, New Delhi, India
关键词
Anti D; Children; Immune thrombocytopenic purpura; INTRAVENOUS IMMUNOGLOBULIN; RANDOMIZED-TRIAL; PLATELET COUNT; GLOBULIN; ADULTS;
D O I
10.1007/s13312-010-0093-3
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
This study was conducted in 20 children (16 males) (mean age 9.2 +/- 4.34y) with immune thrombocytopenic purpura (ITP) to assess the response to anti-D immunoglobulin. Six patients had newly diagnosed ITP, 6 had persistent ITP and 8 had chronic ITP. The overall response rate was 70% (14/20). The median time to response was 3 days (1-13 days). Response to anti-D was not related to age, sex, severity of bleeding, platelet counts at presentation, ABO blood group, or prior steroid or IVIG response.
引用
收藏
页码:517 / 519
页数:3
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