Coenzyme A analogues and derivatives: Synthesis and applications as mechanistic probes of coenzyme A ester-utilizing enzymes

被引：77

作者：

Mishra, PK ^{[1
]}

Drueckhammer, DG ^{[1
]}

机构：

[1] SUNY Stony Brook, Dept Chem, Stony Brook, NY 11794 USA

来源：

CHEMICAL REVIEWS | 2000年 / 100卷 / 09期

关键词：

D O I：

10.1021/cr990010m

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A review is given on the synthesis of coenzyme A (CoA), its esters, and analogues and the application of these compounds in studies of CoA ester-utilizing enzymes. Focus is on unnatural derivatives that have been designed for specific interaction with one or a group of CoA or CoA ester-utilizing enzymes. Examples starting in the 1960s are presented.

引用

页码：3283 / 3309

页数：27

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