Tissue distribution of the antigenic variants of canine parvovirus type 2 in dogs

被引：28
作者：
Decaro, Nicola
Martella, Vito
Elia, Gabriella
Desario, Costantina
Campolo, Marco
Lorusso, Eleonora
Colaianni, Maria Loredana
Lorusso, Alessio
Buonavoglia, Canio
机构：
[1] Fac Vet Med Bari, Dept Anim Hlth & Well Being, I-70010 Bari, Italy
[2] DVM, Bari, Italy
来源：
VETERINARY MICROBIOLOGY | 2007年 / 121卷 / 1-2期
关键词：
dog; parvovirus; real-time PCR; tissue distribution;
D O I：
10.1016/j.vetmic.2006.11.005
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Twelve dogs dead as consequence of natural infection caused by canine parvovirus (CPV) type 2a (n = 4), type 2b (n = 4) or type 2c (n = 4) were investigated for determining the viral DNA loads in different tissue samples. By means of a real-time PCR assay, CPV DNA was detected in all tissues examined, with the highest titres observed in the lymphoid tissue and the lowest loads in the urinary tract. Surprisingly, the nervous tissue was found to contain considerable amounts of CPV nucleic acid. Similar patterns of tissue distribution were observed in all the examined dogs irrespective of the antigenic variant causing the disease. (c) 2006 Elsevier B.V. All rights reserved.
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收藏
页码：39 / 44
页数：6
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