Helically Chiral 1-Sulfur-Functionalized [6]Helicene: Synthesis, Optical Resolution, and Functionalization

被引：19
作者：
Tsujihara, Tetsuya [1 ]
Zhou, Da-Yang [2 ]
Suzuki, Takeyuki [2 ]
Tamura, Satoru [1 ]
Kawano, Tomikazu [1 ]
机构：
[1] Iwate Med Univ, Sch Pharm, Dept Med & Organ Chem, Yahaba, Iwate 0283694, Japan
[2] Osaka Univ, Inst Sci & Ind Res, Comprehens Anal Ctr, Ibaraki 5670047, Japan
来源：
ORGANIC LETTERS | 2017年 / 19卷 / 12期
关键词：
ONE HUNDRED YEARS; CIRCULARLY-POLARIZED LUMINESCENCE; NEWMAN-KWART REARRANGEMENT; ASYMMETRIC-SYNTHESIS; STEREOSELECTIVE SYNTHESES; CARBON-SULFUR; HELICENE; LIGANDS; CARBOHELICENES; CATALYSIS;
D O I：
10.1021/acs.orglett.7b01470
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis and optical resolution of helically chiral 5,6,9,10-tetrahydro-1-[6]helicenethiol and its subsequent transformations to enantiopure 1-sulfur-functionalized [6]helicenes are reported. A novel enantiopure [7]thiahelicene having a thiophene ring at the terminal position of the [6]helicene skeleton was synthesized.
引用
收藏
页码：3311 / 3314
页数：4
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