Side effects of chemotherapy for testicular cancers and post-cancer follow-up

被引：4

作者：

Joly, Florence ^{[1
,2
,3
,4
,5
]}

Ahmed-Lecheheb, Djihane ^{[1
,2
,3
]}

Thiery-Vuillemin, Antoine ^{[6
]}

Orillard, Emeline ^{[6
]}

Coquan, Elodie ^{[1
,2
]}

机构：

[1] UNICANCER, Ctr Francois Baclesse, Clin Res Dept, Ave Gen Harris, F-14076 Caen, France

[2] Med Dept, Ave Gen Harris, F-14076 Caen, France

[3] INSERM, U1086, F-14076 Caen, France

[4] Univ Caen Basse Normandie, UMR S1077, F-14000 Caen, France

[5] CHU Caen, Dept Oncol, F-14000 Caen, France

[6] CHU Jean Minjoz, Dept Oncol Med, Blvd Fleming, F-25030 Besancon, France

来源：

BULLETIN DU CANCER | 2019年 / 106卷 / 09期

关键词：

Testicular cancer; Chemotherapy; Side effects; Late effects; CISPLATIN-BASED CHEMOTHERAPY; LONG-TERM SURVIVORS; COGNITIVE IMPAIRMENT; METABOLIC SYNDROME; PULMONARY-FUNCTION; CARDIAC-FUNCTION; PREVALENCE; MORBIDITY; BLEOMYCIN; DIAGNOSIS;

D O I：

10.1016/j.bulcan.2019.04.004

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Testicular cancers are the most frequent and the most curable cancers in young men. Treatments of these cancers represent a great success with cure rote over to 95 %. However, chemotherapy side effects may occur during or after several years post-treatment. This review aimed to highlight complications and physical and psychological side effects occurring mainly after chemotherapy treatment for testicular cancer, and to propose a personalized post-cancer plan specific for patients treated for testicular cancer. Treatments of these cancers can cause short-term complications (asthenia, nausea, vomiting, alapecia..). These side effects disappear within a few months after the end of the treatments. Late complications may occur several years post-treatment. Cardiovascular disease, metabolic syndrome and secondary neaplasia represent the most severe late effects among patients treated for testicular cancer. Given the increased incidence of these chemotherapy-induced side effects, it is indispensable to establish a specific follow up which must include a particular vigilance on the risk of occurrence of second cancer, a follow-up of the cardio-vascular risk factors, pulmonary and auditory follow-up, and early detection of psychosocial disorders.

引用

页码：805 / 811

页数：7

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