Putting the lid on phosphodiesterase 4

被引：36

作者：

Houslay, Miles D. ^{[1
]}

Adams, David R. ^{[2
]}

机构：

[1] Univ Glasgow, Dept Neurosci & Mol Pharmacol, Glasgow G12 8QQ, Lanark, Scotland

[2] Heriot Watt Univ, Dept Chem, Edinburgh EH14 4AS, Midlothian, Scotland

来源：

NATURE BIOTECHNOLOGY | 2010年 / 28卷 / 01期

关键词：

TRIGGERS;

D O I：

10.1038/nbt0110-38

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Structural insights into the regulation of phosphodiesterase 4 lead to the discovery of allosteric modulators with reduced side effects.

引用

页码：38 / 40

页数：3

共 12 条

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