6-Bromo-1-[2-(2-oxo-1,3-oxazolidin-3-yl)ethyl]-1H-imidazo[4,5-b]pyridin-2(3H)-one

被引：2

作者：

Bel-Ghacham, H. ^{[2
]}

Rodi, Y. Kandri ^{[2
]}

Saffon, Natalie ^{[3
]}

Essassi, El Mokhtar ^{[4
]}

Ng, Seik Weng ^{[1
]}

机构：

[1] Univ Malaya, Dept Chem, Kuala Lumpur 50603, Malaysia

[2] Univ Sidi Mohamed Ben Abdallah, Lab Chim Organ Appl, Fac Sci & Tech, Fes, Morocco

[3] Univ Toulouse 3, Serv Commun Rayons X, FR2599, Toulouse, France

[4] Univ Mohammed V Agdal, Lab Chim Organ Heterocycl, Rabat, Morocco

来源：

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2010年 / 66卷

关键词：

Data-to-parameter ratio = 12.6; Mean σ(C-C) = 0.005 Å; R factor = 0.038; Single-crystal X-ray study; T = 173 K; WR factor = 0.077;

D O I：

10.1107/S1600536810002679

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

The title compound, C(11)H(11)BrN(4)O(3), features an ethane fragment substituted with an almost planar (r.m.s. deviation = 0.019 angstrom) imidazo[4,5-b]pyridone ring system and an envelope-shaped oxazolidine unit on separate C atoms. The N-CH(2)-CH(2)-N torsion angle is 52.5 (4)degrees. In the crystal, pairs of molecules are linked by N-H center dot center dot center dot O hydrogen bonds into centrosymmetric dimers.

引用

页码：O456 / U3350

页数：8

共 10 条

[1] [Anonymous], 2005, APEX2 SAINT
[2] Barbour L.J., 2001, J SUPRAMOL CHEM, V1, P189, DOI [DOI 10.1016/S1472-7862(02)00030-8, 10.1016/S1472-7862(02)00030-8]
[3] INOTROPIC A RING SUBSTITUTED SULMAZOLE AND ISOMAZOLE ANALOGS
BARRACLOUGH, P
BLACK, JW
CAMBRIDGE, D
COLLARD, D
FIRMIN, D
GERSKOWITCH, VP
GLEN, RC
GILES, H
HILL, AP
HULL, RAD
IYER, R
KING, WR
KNEEN, CO
LINDON, JC
NOBBS, MS
RANDALL, P
SHAH, GP
SMITH, S
VINE, SJ
WHITING, MV
WILLIAMS, JM
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1990, 33 (08) : 2231 - 2239
[4] BIANCHI M, 1983, EUR J MED CHEM, V18, P501
[5] SYNTHESIS AND ANALGESIC ACTIVITY OF 1,3-DIHYDRO-3-(SUBSTITUTED "PHENYL)IMIDAZO[4,5-B]PYRIDIN-2-ONES AND 3-(SUBSTITUTED PHENYL)-1,2,3-TRIAZOLO[4,5-B]PYRIDINES
CLARK, RL
PESSOLANO, AA
SHEN, TY
JACOBUS, DP
JONES, H
LOTTI, VJ
FLATAKER, LM
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1978, 21 (09) : 965 - 978
[6] NEW ANTIHISTAMINIC N-HETEROCYCLIC 4-PIPERIDINAMINES .3. SYNTHESIS AND ANTIHISTAMINIC ACTIVITY OF N-(4-PIPERIDINYL)-3H-IMIDAZO[4,5-B]PYRIDIN-2-AMINES
JANSSENS, F
TORREMANS, J
JANSSEN, M
STOKBROEKX, RA
LUYCKX, M
JANSSEN, PAJ
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1985, 28 (12) : 1943 - 1947
[7] Sheldrick G.M., 1996, SADABS
[8] A short history of SHELX
Sheldrick, George M.
[J]. ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, 2008, 64 : 112 - 122
[9] SYNTHESIS OF POTENTIAL ANTICANCER AGENTS - IMIDAZO[4,5-C]PYRIDINES AND IMIDAZO[4,5-B]PYRIDINES
TEMPLE, C
ROSE, JD
COMBER, RN
RENER, GA
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1987, 30 (10) : 1746 - 1751
[10] WESTRIP SP, 2010, PUBLCIF UNPUB

← 1 →