Visual association encoding activates the medial temporal lobe: A functional magnetic resonance imaging study

被引：0

作者：

Rombouts, SARB

Machielsen, WCM

Witter, MP

Barkhof, F

Lindeboom, J

Scheltens, P

机构：

[1] Vrije Univ Amsterdam, Grad Sch Neurosci, Inst Neurosci, Dept Clin Phys & Engn, Amsterdam, Netherlands

[2] Vrije Univ Amsterdam, Grad Sch Neurosci, Inst Neurosci, Dept Anat & Embryol, Amsterdam, Netherlands

[3] Vrije Univ Amsterdam, Grad Sch Neurosci, Inst Neurosci, Dept Diagnost Radiol, Amsterdam, Netherlands

[4] Vrije Univ Amsterdam, Grad Sch Neurosci, Inst Neurosci, Dept Psychol, Amsterdam, Netherlands

[5] Vrije Univ Amsterdam, Grad Sch Neurosci, Inst Neurosci, Dept Neurol, Amsterdam, Netherlands

来源：

HIPPOCAMPUS | 1997年 / 7卷 / 06期

关键词：

hippocampus; functional MRI; Alzheimer's disease; neuropsychology;

D O I：

10.1002/(SICI)1098-1063(1997)7:6<594::AID-HIPO2>3.3.CO;2-I

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The involvement of structures in the medial temporal lobe during the encoding of visual associations was studied with functional magnetic resonance imaging. In 11 out of 12 normal healthy volunteers this task resulted in activation in posterior portions of the parahippocampal region, close to the collateral sulcus. In seven subjects activation was encountered in the hippocampal formation. The visual association task as adapted for this study may provide a sensitive measure to study anterograde amnesia prevalent in Alzheimer's disease. Therefore, the present paradigm enables the study of individual changes in learning and memory capacities over time. (C) 1997 Wiley-Liss, Inc.

引用

页码：594 / 601

页数：8

共 29 条

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