Adsorption of a random copolymer at a lipid bilayer membrane

被引:13
|
作者
Ermoshkin, AV
Chen, JZY [1 ]
Lai, PY
机构
[1] Univ Waterloo, Dept Phys, Waterloo, ON N2L 3G1, Canada
[2] Natl Ctr Theoret Sci, Div Phys, Hsinchu 300, Taiwan
[3] Natl Cent Univ, Dept Phys, Chungli 320, Taiwan
[4] Natl Cent Univ, Ctr Complex Syst, Chungli 320, Taiwan
来源
PHYSICAL REVIEW E | 2002年 / 66卷 / 05期
关键词
D O I
10.1103/PhysRevE.66.051912
中图分类号
O35 [流体力学]; O53 [等离子体物理学];
学科分类号
070204 ; 080103 ; 080704 ;
摘要
We examine the conformational properties of a random copolymer, containing a disordered hydrophobic/hydrophilic sequence of monomers, in the presence of a hydrophobic potential well. The model can be used to understand the structural properties of the adsorption of a protein molecule at a lipid-bilayer membrane, and the properties of a random copolymer at the surfaces of a microphase-separated layered polymer structure. Using a trial-potential treatment we demonstrate that a mainly hydrophilic chain may localize on the surface of the bilayer and that a mainly hydrophobic chain may have two typical conformations: localization on the surface or complete adsorption inside the two surfaces.
引用
收藏
页码:6 / 051912
页数:6
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