Adsorption of a random copolymer at a lipid bilayer membrane

被引：14

作者：

Ermoshkin, AV

Chen, JZY ^{[1
]}

Lai, PY

机构：

[1] Univ Waterloo, Dept Phys, Waterloo, ON N2L 3G1, Canada

[2] Natl Ctr Theoret Sci, Div Phys, Hsinchu 300, Taiwan

[3] Natl Cent Univ, Dept Phys, Chungli 320, Taiwan

[4] Natl Cent Univ, Ctr Complex Syst, Chungli 320, Taiwan

来源：

PHYSICAL REVIEW E | 2002年 / 66卷 / 05期

关键词：

D O I：

10.1103/PhysRevE.66.051912

中图分类号：

O35 [流体力学]; O53 [等离子体物理学];

学科分类号：

070204 ; 080103 ; 080704 ;

摘要：

We examine the conformational properties of a random copolymer, containing a disordered hydrophobic/hydrophilic sequence of monomers, in the presence of a hydrophobic potential well. The model can be used to understand the structural properties of the adsorption of a protein molecule at a lipid-bilayer membrane, and the properties of a random copolymer at the surfaces of a microphase-separated layered polymer structure. Using a trial-potential treatment we demonstrate that a mainly hydrophilic chain may localize on the surface of the bilayer and that a mainly hydrophobic chain may have two typical conformations: localization on the surface or complete adsorption inside the two surfaces.

引用

页码：6 / 051912

页数：6

共 22 条

[1] Concentration dependence of the film pressure of human serum albumin at the water/decane interface [J].