A new approach to the synthesis of a key intermediate in the synthesis of lincomycin

被引:6
作者
Prado, MAF [1 ]
Alves, RJ [1 ]
deOliveira, AB [1 ]
deSouza, JD [1 ]
机构
[1] UNIV FED MINAS GERAIS,INST CIENCIAS EXATAS,DEPT QUIM,BR-31270901 BELO HORIZONT,MG,BRAZIL
关键词
D O I
10.1080/00397919608003706
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
6-acetamido-6,8-dideoxy-1,2:3,4-di-O-isopropylidene-D-glycero-alpha-D-galacto-octopyranos-7-ulose (6), has been synthesised from D-galactose. The side chain elongation was carried out by cyano-amination of the protected dialdo sugar (2), followed by N-acetylation, and a subsequent Grignard reaction.
引用
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页码:1015 / 1022
页数:8
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