DNA fuel for free-running nanomachines

被引:290
作者
Turberfield, AJ
Mitchell, JC
Yurke, B
Mills, AP
Blakey, MI
Simmel, FC
机构
[1] Univ Oxford, Dept Phys, Clarendon Lab, Oxford OX1 3PU, England
[2] Bell Labs, Lucent Technol, Murray Hill, NJ 07974 USA
基金
英国工程与自然科学研究理事会;
关键词
D O I
10.1103/PhysRevLett.90.118102
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
We describe kinetic control of DNA hybridization: loop complexes are used to inhibit the hybridization of complementary oligonucleotides; rationally designed DNA catalysts are shown to be effective in promoting their hybridization. This is the basis of a strategy for using DNA as a fuel to drive free-running artificial molecular machines.
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页数:4
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