Chromosome assignment of eight SOX family genes in chicken

被引：19

作者：

Kuroiwa, A

Uchikawa, M

Kamamchi, Y

Kondoh, H

Nishida-Umehara, C

Masabanda, J

Griffin, DK

Matsuda, Y

机构：

[1] Hokkaido Univ, Ctr Adv Sci & Technol, Lab Anim Cytogenet, Kita Ku, Sapporo, Hokkaido 0600810, Japan

[2] Osaka Univ, Grad Sch Frontier Biosci, Dev Biol Lab, Osaka, Japan

[3] Hokkaido Univ, Grad Sch Environm Earth Sci, Div Biosci, Lab Cytogenet, Sapporo, Hokkaido 060, Japan

[4] Hokkaido Univ, Fac Sci, Chromosome Res Unit, Sapporo, Hokkaido 060, Japan

[5] Brunel Univ, Dept Biol Sci, Uxbridge UB8 3PH, Middx, England

来源：

CYTOGENETIC AND GENOME RESEARCH | 2002年 / 98卷 / 2-3期

关键词：

D O I：

10.1159/000069803

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Chromosome locations of the eight SOX family genes, SOX1, SOX2, SOX3, SOX5, SOX9, SOX10, SOX14 and SOX21, were determined in the chicken by fluorescence in situ hybridization. The SOX1 and SOX21 genes were localized to chicken chromosome 1q3.1 --> q3.2, SOX5 to chromosome 1p1.6 --> p1.4, SOX10 to chromosome 1p1.6, and SOX3 to chromosome 4p1.2 --> p1.1. The SOX2 and SOX14 genes were shown to be linked to chromosome 9 using two-colored FISH and chromosome painting, and the SOX9 gene was assigned to a pair of microchromosomes. These results suggest that these SOX genes form at least three clusters on chicken chromosomes. The seven SOX genes, SOX1, SOX2, SOX3, SOX5, SOX10, SOX14 and SOX21 were localized to chromosome segments with homologies to human chromosomes, indicating that the chromosome locations of SOX family genes are highly conserved between chicken and human. Copyright (C) 2002 S. Karger AG, Basel.

引用

页码：189 / 193

页数：5

共 23 条

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