SARS-CoV-2 Vaccination During Pregnancy: A Complex Decision

被引：20

作者：

Wang, Elizabeth Wenqian ^{[1
]}

Parchem, Jacqueline G. ^{[2
]}

Atmar, Robert L. ^{[3
]}

Clark, Eva H. ^{[3
,4
,5
]}

机构：

[1] Univ Maryland, St Joseph Med Ctr, Dept Infect Dis, Towson, MD USA

[2] Univ Texas Hlth Sci Ctr Houston, Dept Obstet Gynecol & Reprod Sci, McGovern Med Sch, Houston, TX 77030 USA

[3] Baylor Coll Med, Dept Med, Sect Infect Dis, Houston, TX 77030 USA

[4] Michael E DeBakey VA Med Ctr, Dept Med, Sect Hlth Serv Res, Ctr Innovat Qual Safety & Effectiveness IQuESt, Houston, TX USA

[5] Baylor Coll Med, Houston, TX 77021 USA

来源：

OPEN FORUM INFECTIOUS DISEASES | 2021年 / 8卷 / 05期

关键词：

breastfeeding; COVID-19; pregnancy; SARS-CoV-2; vaccine; CORONAVIRUS DISEASE 2019; PERINATAL OUTCOMES; INFECTION; VACCINES; COHORT; WOMEN; RISK;

D O I：

10.1093/ofid/ofab180

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

As the first severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines passed UK and US regulatory milestones in late 2020 and early 2021, multiple professional societies offered recommendations to assist pregnant and breastfeeding people as they choose whether to undergo vaccination. Despite such guidance, the lack of data describing vaccine safety, immunogenicity, and efficacy in pregnant and breastfeeding people has made this decision challenging for many. However, even considering the paucity of data, the known risks of coronavirus disease 2019 during pregnancy likely outweigh the not yet fully elucidated risks of SARS-CoV-2 vaccines, which have reassuring safety and efficacy profiles among nonpregnant people.

引用

页数：6

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