Mean phase coherence as a measure for phase synchronization and its application to the EEG of epilepsy patients

被引：1003

作者：

Mormann, F

Lehnertz, K

David, P

Elger, CE

机构：

[1] Univ Bonn, Clin Epileptol, D-53105 Bonn, Germany

[2] Univ Bonn, Inst Radiat & Nucl Phys, D-53115 Bonn, Germany

来源：

PHYSICA D | 2000年 / 144卷 / 3-4期

关键词：

Hilbert transform; mean phase coherence; phase synchronization; electroencephalogram; epilepsy;

D O I：

10.1016/S0167-2789(00)00087-7

中图分类号：

O29 [应用数学];

学科分类号：

070104 ;

摘要：

We apply the concept of phase synchronization of chaotic and/or noisy systems and the statistical distribution of the relative instantaneous phases to electroencephalograms (EEGs) recorded from patients with temporal lobe epilepsy. Using the mean phase coherence as a statistical measure for phase synchronization, we observe characteristic spatial and temporal shifts in synchronization that appear to be strongly related to pathological activity. In particular, we observe distinct differences in the degree of synchronization between recordings from seizure-free intervals and those before an impending seizure, indicating an altered state of brain dynamics prior to seizure activity. (C) 2000 Elsevier Science B.V. All rights reserved.

引用

页码：358 / 369

页数：12

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