Fluorescence detection for DNA using hybridization chain reaction with enzyme-amplification

被引：102

作者：

Niu, Shuyan ^{[1
]}

Jiang, Yu ^{[1
]}

Zhang, Shusheng ^{[1
]}

机构：

[1] Qingdao Univ Sci & Technol, Coll Chem & Mol Engn, Minist Educ, Key Lab Ecochem Engn, Qingdao 266042, Shandong, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 18期

基金：

中国国家自然科学基金;

关键词：

NUCLEIC-ACID; DESIGN; CONSTRUCTION; COMPLEXES; JUNCTIONS; MOLECULES;

D O I：

10.1039/c000166j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A signal amplification based on a combination of hybridization chain reaction (HCR) and enzyme-enhancement was applied in the study of a novel biosensor. The target sequence was added as catalyst which was simply transmitted but did not disappear as the DNA double strand grew on the surface of magnetic beads (MBs).

引用

收藏

页码：3089 / 3091

页数：3

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