A huge adenosquamous carcinoma of the pancreas with sarcomatoid change: An unusual case report

被引：12
作者：
Lu, Bao-Chun [1 ]
Wang, Chen [2 ]
Yu, Jian-Hua [1 ]
Shen, Zhi-Hong [1 ]
Yang, Jian-Hui [1 ]
机构：
[1] Zhejiang Univ, Dept Gen Surg, Shaoxing Peoples Hosp, Shaoxing Hosp, Shaoxing 312000, Zhejiang, Peoples R China
[2] Zhejiang Univ, Dept Pathol, Shaoxing Peoples Hosp, Shaoxing Hosp, Shaoxing 312000, Zhejiang, Peoples R China
来源：
WORLD JOURNAL OF GASTROENTEROLOGY | 2014年 / 20卷 / 43期
关键词：
Adenosquamous carcinoma; Sarcomatoid change; Pancreatic tumors; Histopathological types; Epithelial-mesenchymal transition; EPITHELIAL-MESENCHYMAL TRANSITIONS; CARCINOSARCOMA; FEATURES; CELLS;
D O I：
10.3748/wjg.v20.i43.16381
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Adenosquamous carcinoma rarely occurs in the pancreas, and is characterized by the presence of cellular components from both duct adenocarcinoma and squamous carcinoma. Here, we describe a rare case of pancreatic adenosquamous carcinoma with sarcomatous change. Immunohistochemistry showed that the sarcomatous lesion lost the epithelial marker and aberrantly expressed of acquired mesenchymal markers, which indicated that this special histological phenotype may be attributed to epithelial-mesenchymal transition. This case also indicated that a routine radical surgery without aggressive treatment strategies was still appropriate for adenosquamous carcinoma of the pancreas with sarcomatoid change. (C) 2014 Baishideng Publishing Group Inc. All rights reserved.
引用
收藏
页码：16381 / 16386
页数：6
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