The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms

被引：2309

作者：

Alaggio, Rita ^{[1
]}

Amador, Catalina ^{[2
]}

Anagnostopoulos, Ioannis ^{[3
,36
]}

Attygalle, Ayoma D. ^{[4
]}

Araujo, Iguaracyra Barreto de Oliveira ^{[5
]}

Berti, Emilio ^{[6
]}

Bhagat, Govind ^{[7
]}

Borges, Anita Maria ^{[8
]}

Boyer, Daniel ^{[9
]}

Calaminici, Mariarita ^{[10
]}

Chadburn, Amy ^{[11
]}

Chan, John K. C. ^{[12
]}

Cheuk, Wah ^{[12
]}

Chng, Wee-Joo ^{[13
]}

Choi, John K. ^{[14
]}

Chuang, Shih-Sung ^{[15
]}

Coupland, Sarah E. ^{[16
]}

Czader, Magdalena ^{[17
]}

Dave, Sandeep S. ^{[18
,19
]}

de Jong, Daphne ^{[20
]}

Du, Ming-Qing ^{[21
]}

Elenitoba-Johnson, Kojo S. ^{[22
]}

Ferry, Judith ^{[23
,24
]}

Geyer, Julia ^{[11
]}

Gratzinger, Dita ^{[25
]}

Guitart, Joan ^{[26
]}

Gujral, Sumeet ^{[27
]}

Harris, Marian ^{[28
]}

Harrison, Christine J. ^{[29
]}

Hartmann, Sylvia ^{[30
]}

Hochhaus, Andreas ^{[31
]}

Jansen, Patty M. ^{[32
]}

Karube, Kennosuke ^{[33
]}

Kempf, Werner ^{[34
,35
]}

Khoury, Joseph ^{[36
]}

Kimura, Hiroshi ^{[37
]}

Klapper, Wolfram ^{[38
,39
]}

Kovach, Alexandra E. ^{[40
]}

Kumar, Shaji ^{[41
]}

Lazar, Alexander J. ^{[42
,43
]}

Lazzi, Stefano ^{[44
]}

Leoncini, Lorenzo ^{[44
]}

Leung, Nelson ^{[45
]}

Leventaki, Vasiliki ^{[46
]}

Li, Xiao-Qiu ^{[47
]}

Lim, Megan S. ^{[22
]}

Liu, Wei-Ping ^{[48
]}

Louissaint, Abner, Jr. ^{[23
,24
]}

Marcogliese, Andrea ^{[49
,50
]}

Medeiros, L. Jeffrey ^{[36
]}

机构：

[1] IRCCS, Bambino Gesu Childrens Hosp, Dept Labs, Pathol Unit, Rome, Italy

[2] Univ Miami, Dept Pathol, Miami, FL USA

[3] Julius Maximilians Univ Wurzburg, Inst Pathol, Wurzburg, Germany

[4] Royal Marsden Hosp, Dept Histopathol, London, England

[5] Fed Univ Bahia UFBA, Dept Pathol, Salvador, BA, Brazil

[6] Univ Milan, Osped Maggiore Policlin, IRCCS, Fdn Ca Granda, Milan, Italy

[7] Columbia Univ, Dept Pathol & Cell Biol, Irving Med Ctr, New York, NY USA

[8] SL Raheja Hosp, Div Histopathol, Mumbai, Maharashtra, India

[9] Univ Michigan, Dept Pathol, Ann Arbor, MI 48109 USA

[10] QMUL & SIHMDS Barts Hlth NHS Trust, Barts Canc Inst, Ctr Haematooncol, London, England

[11] Weill Cornell Med, Dept Pathol & Lab Med, New York, NY USA

[12] Queen Elizabeth Hosp, Dept Pathol, Kowloon, Hong Kong, Peoples R China

[13] Natl Univ Canc Inst, Singapore, Singapore

[14] Univ Alabama Birmingham, Dept Pathol, Birmingham, AL 35294 USA

[15] Chi Mei Med Ctr, Dept Pathol, Tainan, Taiwan

[16] Liverpool Univ Hosp Fdn Trust, Liverpool Clin Labs, Liverpool, Merseyside, England

[17] Indiana Univ, Dept Pathol & Lab Med, Indianapolis, IN 46204 USA

[18] Duke Univ, Ctr Genom & Computat Biol, Durham, NC USA

[19] Duke Univ, Dept Med, Durham, NC USA

[20] Locat Vrije Univ Amsterdam, Amsterdam UMC, Dept Pathol, Amsterdam, Netherlands

[21] Univ Cambridge, Dept Pathol, Div Cellular & Mol Biol, Cambridge, England

[22] Univ Penn, Dept Pathol & Lab Med, Philadelphia, PA USA

[23] Massachusetts Gen Hosp, Dept Pathol, Boston, MA 02114 USA

[24] Harvard Med Sch, Boston, MA 02115 USA

[25] Stanford Univ, Dept Pathol, Sch Med, Stanford, CA 94305 USA

[26] Northwestern Univ, Feinberg Med Sch, Dept Dermatol, Chicago, IL 60611 USA

[27] Tata Mem Hosp, Dept Pathol, Mumbai, Maharashtra, India

[28] Boston Childrens Hosp, Dept Pathol, Boston, MA USA

[29] Newcastle Univ, Translat & Clin Res Inst, Ctr Canc, Fac Med Sci, Newcastle Upon Tyne, Tyne & Wear, England

[30] Goethe Univ Frankfurt, Dr Senckenberg Inst Pathol, Frankfurt, Germany

[31] Univ Klinikum Jena, Hematol Oncol, Jena, Germany

[32] Leiden Univ, Med Ctr, Dept Pathol, Leiden, Netherlands

[33] Dept Pathol & Lab Med, Nagoya, Aichi, Japan

[34] Kempf & Pfaltz Histol Diagnost Zurich, Zurich, Switzerland

[35] Univ Hosp Zurich, Dept Dermatol, Zurich, Switzerland

[36] Univ Texas MD Anderson Canc Ctr, Div Pathol & Lab Med, Dept Hematopathol, Houston, TX 77030 USA

[37] Nagoya Univ, Grad Sch Med, Dept Virol, Nagoya, Aichi, Japan

[38] Univ Kiel, Univ Hosp Schleswig Holstein, Dept Pathol, Hematopathol Sect, Kiel, Germany

[39] Univ Kiel, Lymph Node Registry, Kiel, Germany

[40] Childrens Hosp Los Angeles, Dept Pathol & Lab Med, Los Angeles, CA 90027 USA

[41] Mayo Clin, Div Hematol, Rochester, MN USA

[42] Univ Texas MD Anderson Canc Ctr, Dept Pathol, Houston, TX 77030 USA

[43] Univ Texas MD Anderson Canc Ctr, Dept Genom Med, Houston, TX 77030 USA

[44] Univ Siena, Dept Med Biotechnol, Siena, Italy

[45] Mayo Clin, Div Hematol, Div Nephrol & Hypertens, Rochester, MN USA

[46] Med Coll Wisconsin & Childrens Wisconsin, Dept Pathol, Milwaukee, WI USA

[47] Fudan Univ, Dept Pathol, Shanghai Canc Ctr, Shanghai, Peoples R China

[48] Sichuan Univ, Dept Pathol, West China Hosp, Chengdu, Peoples R China

[49] Baylor Coll Med, Dept Pathol & Immunol, Houston, TX 77030 USA

[50] Texas Childrens Hosp, Houston, TX 77030 USA

来源：

LEUKEMIA | 2022年 / 36卷 / 07期

关键词：

ACUTE LYMPHOBLASTIC-LEUKEMIA; T-CELL-LYMPHOMA; CHRONIC LYMPHOCYTIC-LEUKEMIA; PREDOMINANT HODGKIN LYMPHOMA; MULTICENTRIC CASTLEMAN DISEASE; DIFFUSE FOLLICULAR LYMPHOMA; LYMPHOPROLIFERATIVE DISEASE; CLINICOPATHOLOGICAL FEATURES; LYMPHOPLASMACYTIC LYMPHOMA; GENETIC ALTERATIONS;

D O I：

10.1038/s41375-022-01620-2

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We herein present an overview of the upcoming 5(th) edition of the World Health Organization Classification of Haematolymphoid Tumours focussing on lymphoid neoplasms. Myeloid and histiocytic neoplasms will be presented in a separate accompanying article. Besides listing the entities of the classification, we highlight and explain changes from the revised 4(th) edition. These include reorganization of entities by a hierarchical system as is adopted throughout the 5(th) edition of the WHO classification of tumours of all organ systems, modification of nomenclature for some entities, revision of diagnostic criteria or subtypes, deletion of certain entities, and introduction of new entities, as well as inclusion of tumour-like lesions, mesenchymal lesions specific to lymph node and spleen, and germline predisposition syndromes associated with the lymphoid neoplasms.

引用

页码：1720 / 1748

页数：29

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