A cost-effectiveness analysis of Japanese encephalitis vaccine in Cambodia

被引:35
作者
Touch, Sok
Suraratdecha, Chutima [1 ]
Samnang, Chham
Heng, Seng
Gazley, Lauren [1 ]
Huch, Chea
Sovann, Ly
Chhay, Chab Seak
Soeung, Sann Chan
机构
[1] PATH, Seattle, WA 98121 USA
基金
比尔及梅琳达.盖茨基金会;
关键词
Japanese encephalitis; SA; 14-14-2; Cambodia; NEPALESE CHILDREN; IMMUNIZATION;
D O I
10.1016/j.vaccine.2010.04.086
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
This study aimed to evaluate the cost and effectiveness of introducing a live, attenuated vaccine (SA 14-14-2) against Japanese encephalitis (JE) into the immunization program. The study demonstrated that SA 14-14-2 immunization is cost-effective in controlling JE in Cambodia compared to no vaccination. Averting one disability-adjusted life year, from a societal perspective, through the introduction of SA 14-14-2 through routine immunization, or a combination of routine immunization plus a campaign targeting children 1-5 or 1-10 years of age, costs US$22. US$34 and US$53, respectively. Sensitivity analyses confirmed that there was a high probability of SA 14-14-2 immunization being cost-effective under conditions of uncertainty. (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码:4593 / 4599
页数:7
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