Epidemiology of COVID-19 in Tehran, Iran: A Cohort Study of Clinical Profile, Risk Factors, and Outcomes

被引：14

作者：

Hatamabadi, Hamidreza ^{[1
]}

Sabaghian, Tahereh ^{[2
]}

Sadeghi, Amir ^{[3
]}

Heidari, Kamran ^{[4
]}

Safavi-Naini, Seyed Amir Ahmad ^{[5
]}

Looha, Mehdi Azizmohammad ^{[6
]}

Taraghikhah, Nazanin ^{[3
]}

Khalili, Shayesteh ^{[7
]}

Karrabi, Keivan ^{[8
]}

Saffarian, Afsaneh ^{[9
]}

Shahsavan, Saba ^{[5
]}

Majlesi, Hossein ^{[5
]}

Allahgholipour Komleh, Amirreza ^{[10
]}

Hatari, Saba ^{[5
]}

Zameni, Nadia ^{[5
]}

Ilkhani, Saba ^{[5
]}

Hajimirzaei, Shideh Moftakhari ^{[5
]}

Ghaffari, Aydin ^{[5
]}

Fallah, Mohammad Mahdi ^{[5
]}

Kalantar, Reyhaneh ^{[5
]}

Naderi, Nariman ^{[5
]}

Bahmaei, Parnian ^{[5
]}

Asadimanesh, Naghmeh ^{[5
]}

Esbati, Romina ^{[5
]}

Yazdani, Omid ^{[5
]}

Shojaeian, Fatemeh ^{[5
]}

Azizan, Zahra ^{[5
]}

Ebrahimi, Nastaran ^{[5
]}

Jafarzade, Fateme ^{[5
]}

Soheili, Amirali ^{[11
]}

Gholampoor, Fatemeh ^{[5
]}

Namazi, Negarsadat ^{[5
]}

Solhpour, Ali ^{[12
]}

Jamialahamdi, Tannaz ^{[13
]}

Pourhoseingholi, Mohamad Amin ^{[6
]}

Sahebkar, Amirhossein ^{[14
,15
,16
]}

机构：

[1] Shahid Beheshti Univ Med Sci, Imam Hossein Hosp, Sch Med, Dept Emergency Med, Tehran, Iran

[2] Shahid Beheshti Univ Med Sci, Imam Hossein Hosp, Chron Kidney Dis Res Ctr CKDRC, Tehran, Iran

[3] Shahid Beheshti Univ Med Sci, Res Inst Gastroenterol & Liver Dis, Gastroenterol & Liver Dis Res Ctr, Tehran, Iran

[4] Shahid Beheshti Univ Med Sci, Shohada Etajrish Hosp, Skull Base Res Ctr, Tehran, Iran

[5] Shahid Beheshti Univ Med Sci, Sch Med, Tehran, Iran

[6] Shahid Beheshti Univ Med Sci, Res Inst Gastroenterol & Liver Dis, Basic & Mol Epidemiol Gastrointestinal Disorders R, Tehran, Iran

[7] Shahid Beheshti Univ Med Sci, Imam Hossein Hosp, Sch Med, Dept Internal Med, Tehran, Iran

[8] Shahid Beheshti Univ Med Sci, Shohadaye Tajrish Hosp, Dept Emergency Med, Tehran, Iran

[9] Shaheed Beheshti Univ Med Sci, Loghman Hakim Hosp, Dept Internal Med, Tehran, Iran

[10] Shahid Beheshti Univ Med Sci, Student Res Comm, Sch Nursing & Midwifery, Tehran, Iran

[11] Shahid Beheshti Univ Med Sci, Students Res Comm, Sch Med, Tehran, Iran

[12] Univ Florida, Dept Anesthesiol, Gainesville, FL USA

[13] Mashhad Univ Med Sci, Surg Oncol Res Ctr, Mashhad, Iran

[14] Mashhad Univ Med Sci, Appl Biomed Res Ctr, Mashhad, Iran

[15] Mashhad Univ Med Sci, Pharmaceut Technol Inst, Biotechnol Res Ctr, Mashhad, Iran

[16] Mashhad Univ Med Sci, Sch Pharm, Dept Biotechnol, Mashhad, Iran

来源：

BIOMED RESEARCH INTERNATIONAL | 2022年 / 2022卷

关键词：

D O I：

10.1155/2022/2350063

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Background. The outbreak of coronavirus disease 2019 (COVID-19) dates back to December 2019 in China. Iran has been among the most prone countries to the virus. The aim of this study was to report demographics, clinical data, and their association with death and CFR. Methods. This observational cohort study was performed from 20th March 2020 to 18th March 2021 in three tertiary educational hospitals in Tehran, Iran. All patients were admitted based on the WHO, CDC, and Iran's National Guidelines. Their information was recorded in their medical files. Multivariable analysis was performed to assess demographics, clinical profile, outcomes of disease, and finding the predictors of death due to COVID-19. Results. Of all 5318 participants, the median age was 60.0 years, and 57.2% of patients were male. The most significant comorbidities were hypertension and diabetes mellitus. Cough, dyspnea, and fever were the most dominant symptoms. Results showed that ICU admission, elderly age, decreased consciousness, low BMI, HTN, IHD, CVA, dialysis, intubation, Alzheimer disease, blood injection, injection of platelets or FFP, and high number of comorbidities were associated with a higher risk of death related to COVID-19. The trend of CFR was increasing (WPC: 1.86) during weeks 25 to 51. Conclusions. Accurate detection of predictors of poor outcomes helps healthcare providers in stratifying patients, based on their risk factors and healthcare requirements to improve their survival chance.

引用

页数：17

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