Beyond boundaries-Eph:ephrin signaling in neurogenesis

被引：34
|
作者：
Laussu, J. [1 ]
Khuong, A. [2 ]
Gautrais, J. [3 ]
Davy, A. [1 ]
机构：
[1] Univ Toulouse, CNRS, Ctr Biol Dev, Toulouse, France
[2] Univ Libre Bruxelles, Unit Social Ecol, Brussels, Belgium
[3] Univ Toulouse, CNRS, Ctr Rech Cognit Anim, Toulouse, France
来源：
CELL ADHESION & MIGRATION | 2014年 / 8卷 / 04期
关键词：
adult stem cells; development; Eph receptors; ephrin; model; neocortex; neural progenitors; neurogenesis; population dynamics; SGZ; SVZ; NEURAL PRECURSOR CELLS; STEM-CELL; EPHRIN-B; HIPPOCAMPAL NEUROGENESIS; SUBVENTRICULAR ZONE; ADULT NEUROGENESIS; CEREBRAL-CORTEX; SELF-RENEWAL; PROLIFERATION; RECEPTORS;
D O I：
10.4161/19336918.2014.969990
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Eph:ephrin signaling plays an important role in embryonic development as well as tissue homeostasis in the adult. At the cellular level, this transduction pathway is best known for its role in the control of cell adhesion and repulsion, cell migration and morphogenesis. Yet, a number of publications have also implicated Eph:ephrin signaling in the control of adult and embryonic neurogenesis. As is the case for other biological processes, these studies have reported conflicting and sometimes opposite roles for Eph:ephrin signaling in neurogenesis. Herein, we review these studies and we discuss existing mathematical models of stem cell dynamics and neurogenesis that provide a coherent framework and may help reconcile conflicting results.
引用
收藏
页码：349 / 359
页数：11
相关论文
共 50 条
  • [1] Regulation of cell differentiation by Eph receptor and ephrin signaling
    Wilkinson, David G.
    CELL ADHESION & MIGRATION, 2014, 8 (04) : 339 - 348
  • [2] Eph/ephrin recognition and the role of Eph/ephrin clusters in signaling initiation
    Nikolov, Dimitar B.
    Xu, Kai
    Himanen, Juha P.
    BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 2013, 1834 (10): : 2160 - 2165
  • [3] Eph/ephrin signaling in the kidney and lower urinary tract
    Weiss, Anna-Carina
    Kispert, Andreas
    PEDIATRIC NEPHROLOGY, 2016, 31 (03) : 359 - 371
  • [4] Eph/ephrin signaling: networks
    Arvanitis, Dina
    Davy, Alice
    GENES & DEVELOPMENT, 2008, 22 (04) : 416 - 429
  • [5] Til Eph Do Us Part: Intercellular Signaling via Eph Receptors and Ephrin Ligands Guides Cerebral Cortical Development from Birth Through Maturation
    North, Hilary A.
    Clifford, Meredith A.
    Donoghue, Maria J.
    CEREBRAL CORTEX, 2013, 23 (08) : 1765 - 1773
  • [6] Eph/Ephrin Signaling in the Tumor Microenvironment
    Ieguchi, Katsuaki
    Maru, Yoshiro
    TUMOR MICROENVIRONMENT: SIGNALING PATHWAYS, PT B, 2021, 1270 : 45 - 56
  • [7] Eph/Ephrin Signaling in Injury and Inflammation
    Coulthard, Mark G.
    Morgan, Michael
    Woodruff, Trent M.
    Arumugam, Thiruma V.
    Taylor, Stephen M.
    Carpenter, Todd C.
    Lackmann, Martin
    Boyd, Andrew W.
    AMERICAN JOURNAL OF PATHOLOGY, 2012, 181 (05): : 1493 - 1503
  • [8] Eph/ephrin signaling: Genetic, phosphoproteomic, and transcriptomic approaches
    Bush, Jeffrey O.
    Soriano, Philippe
    SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, 2012, 23 (01) : 26 - 34
  • [9] Eph/ephrin molecules-a hub for signaling and endocytosis
    Pitulescu, Mara E.
    Adams, Ralf H.
    GENES & DEVELOPMENT, 2010, 24 (22) : 2480 - 2492
  • [10] Eph and ephrin signaling in the formation of topographic maps
    Triplett, Jason W.
    Feldheim, David A.
    SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, 2012, 23 (01) : 7 - 15
12345