In-hospital outcomes of COVID-19 ST-elevation myocardial infarction patients

被引：64

作者：

Rodriguez-Leor, Oriol ^{[1
,2
,3
]}

Cid-Alvarez, Belen ^{[4
]}

Prado, Armando Perez de ^{[5
]}

Rossello, Xavier ^{[6
,7
]}

Ojeda, Soledad ^{[8
]}

Serrador, Ana ^{[2
,9
]}

Lopez-Palop, Ramon ^{[10
]}

Martin-Moreiras, Javier ^{[2
,11
]}

Rumoroso, Jose Ramon ^{[12
]}

Cequier, Angel ^{[13
]}

Ibanez, Borja ^{[2
]}

Cruz-Gonzalez, Ignacio ^{[2
]}

Romaguera, Rafael ^{[13
]}

Moreno, Raul ^{[2
,14
]}

机构：

[1] Hosp Badalona Germans Trias & Pujol, Inst Cor, Carretera Canyet SN, Badalona 08916, Spain

[2] Inst Salud Carlos III, CIBER Enfermedades Cardiovasc CIBERCV, Madrid, Spain

[3] Inst Rec Ciencies Salut Germans Trias & Pujol, Badalona, Spain

[4] Hosp Clin Santiago Compostela, Cardiol Dept, Santiago De Compostela, Spain

[5] Hosp Leon, Cardiol Dept, Leon, Spain

[6] Ctr Nacl Invest Cardiovasc Carl III CNIC, Madrid, Spain

[7] Hosp Univ Son Espases, Hlth Res Inst Balear Isl IdISBa, Cardiol Dept, Palma De Mallorca, Spain

[8] Univ Cordoba, Hosp Univ Reina Sofia, IMIBIC, Cardiol Dept, Cordoba, Spain

[9] Hosp Clin Valladolid, Cardiol Dept, Valladolid, Spain

[10] Hosp Virgen Arrixaca, Cardiol Dept, Murcia, Spain

[11] Hosp Univ Salamanca, IBSAL, Cardiol Dept, Salamanca, Spain

[12] Hosp GaldakaoUsansolo, Cardiol Dept, Galdakao, Vizcaya, Spain

[13] Univ Barcelona, Hosp Bellvitge IDIBELL, Cardiol Dept, Barcelona, Spain

[14] Hosp La Paz, Cardiol Dept, Madrid, Spain

来源：

EUROINTERVENTION | 2021年 / 16卷 / 17期

关键词：

clinical research; miscellaneous; STEMI;

D O I：

10.4244/EIJ-D-20-00935

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Aims: The aim of this study was to assess clinical and prognosis differences in patients with COVID-19 and STEMI. Methods and results: Using a nationwide registry of consecutive patients managed within 42 specific STEMI care networks, we compared patient and procedure characteristics and in-hospital outcomes in two different cohorts, according to whether or not they had COVID-19. Among 1,010 consecutive STEMI patients, 91 were identified as having COVID-19 (9.0%). With the exception of smoking status (more frequent in non-COVID-19 patients) and previous coronary artery disease (more frequent in COVID-19 patients), clinical characteristics were similar between the groups, but COVID-19 patients had more heart failure on arrival (31.9% vs 18.4%, p=0.002). Mechanical thrombectomy (44% vs 33.5%, p=0.046) and GP IIb/IIIa inhibitor administration (20.9% vs 11.2%, p=0.007) were more frequent in COVID-19 patients, who had an increased in-hospital mortality (23.1% vs 5.7%, p<0.0001), that remained consistent after adjustment for age, sex, Killip class and ischaemic time (OR 4.85, 95% CI: 2.04-11.51; p<0.001). COVID-19 patients had an increase of stent thrombosis (3.3% vs 0.8%, p=0.020) and cardiogenic shock development after PCI (9.9% vs 3.8%, p=0.007). Conclusions: Our study revealed a significant increase in in-hospital mortality, stent thrombosis and cardiogenic shock development after PCI in patients with STEMI and COVID-19 in comparison with contemporaneous non-COVID-19 STEMI patients. Methods and results: Using a nationwide registry of consecutive patients managed within 42 specific STEMI care networks, we compared patient and procedure characteristics and in-hospital outcomes in two different cohorts, according to whether or not they had COVID-19. Among 1,010 consecutive STEMI patients, 91 were identified as having COVID-19 (9.0%). With the exception of smoking status (more frequent in non-COVID-19 patients) and previous coronary artery disease (more frequent in COVID-19 patients), clinical characteristics were similar between the groups, but COVID-19 patients had more heart failure on arrival (31.9% vs 18.4%, p=0.002). Mechanical thrombectomy (44% vs 33.5%, p=0.046)

引用

页码：1426 / +

页数：12

共 15 条

[11]

Rodríguez-Leor O, 2020, REV ESP CARDIOL, V73, P994, DOI [10.1016/j.recesp.2020.07.033, 10.1016/j.rec.2020.08.002]

[12]

Romaguera R, 2020, REC INTERV CARDIOL, V2, P112

[13] ST-Elevation Myocardial Infarction in Patients With COVID-19 Clinical and Angiographic Outcomes [J].

Stefanini, Giulio G. ;

Montorfano, Matteo ;

Trabattoni, Daniela ;

Andreini, Daniele ;

Ferrante, Giuseppe ;

Ancona, Marco ;

Metra, Marco ;

Curello, Salvatore ;

Maffeo, Diego ;

Pero, Gaetano ;

Cacucci, Michele ;

Assanelli, Emilio ;

Bellini, Barbara ;

Russo, Filippo ;

Ielasi, Alfonso ;

Tespili, Maurizio ;

Danzi, Gian Battista ;

Vandoni, Pietro ;

Bollati, Mario ;

Barbieri, Lucia ;

Oreglia, Jacopo ;

Lettieri, Corrado ;

Cremonesi, Alberto ;

Carugo, Stefano ;

Reimers, Bernhard ;

Condorelli, Gianluigi ;

Chieffo, Alaide .

CIRCULATION, 2020, 141 (25) :2113-2116

[14]

Vivas D, 2020, REV ESP CARDIOL, V73, P749, DOI [10.1016/j.recesp.2020.04.006, 10.1016/j.rec.2020.04.025]

[15] Catheterization Laboratory Considerations During the Coronavirus (COVID-19) Pandemic From the ACC's Interventional Council and SCAI [J].

Welt, Frederick G. P. ;

Shah, Pinak B. ;

Aronow, Herbert D. ;

Bortnick, Anna E. ;

Henry, Timothy D. ;

Sherwood, Matthew W. ;

Young, Michael N. ;

Davidson, Laura J. ;

Kadavath, Sabeeda ;

Mahmud, Ehtisham ;

Kirtane, Ajay J. .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2020, 75 (18) :2372-2375

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