Meglumine catalyzed one pot synthesis of new fluorescent 2-amino-4-pyrazolyl-6-aryldiazenyl-4H-chromene-3-carbonitriles

被引：7

作者：

Korade, Suyog N. ^{[1
]}

Mhaldar, Pradeep M. ^{[1
]}

Kulkarni, Prafulladatta P. ^{[2
]}

Rashinkar, Gajanan S. ^{[1
]}

Pore, Dattaprasad M. ^{[1
]}

机构：

[1] Shivaji Univ, Dept Chem, Kolhapur 416004, Maharashtra, India

[2] Gogate Jogalekar Coll, Dept Chem, Ratnagiri, India

来源：

SYNTHETIC COMMUNICATIONS | 2021年 / 51卷 / 15期

关键词：

Diazo compounds; green chemistry; heterocycles; multicomponent reaction; optical properties; THROUGHPUT SCREENING ASSAY; ACTIVE METHYLENE; ANTITUMOR EVALUATION; DERIVATIVES; DISCOVERY; SERIES; 4-ARYL-4H-CHROMENES; SALICYLALDEHYDES; CHEMISTRY; PROBE;

D O I：

10.1080/00397911.2021.1934875

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Meglumine, a biodegradable basic organo-catalyst has been efficiently explored for the one-pot synthesis of new fluorescent 2-amino-4-(5-hydroxy-3-methyl-1H-pyrazol-4-yl)-6-aryldiazenyl-4H-chromene-3-carbonitriles in an aqueous medium at room temperature. The synthesized compounds were found highly fluorescent when screened for photoluminescence properties. The planar structure equipped with substituted aryldiazenyl group led to the extension of conjugation that facilitated fluorescence emission in the visible region with a large stokes shift of 290-294 nm. The novelty of work is a synthesis of highly conjugated molecular assembly, high yield in shorter reaction time, energy efficiency, atom economy, utilization of water as a universal green solvent and meglumine as an eco-benign organo-catalyst.

引用

页码：2336 / 2348

页数：13

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