A simple and rapid technique for recovery of 99mTc from low specific activity (n,γ)99Mo based on solvent extraction and column chromatography

被引：25
作者：
Chattopadhyay, Sankha [1 ]
Das, Sujata Saha [1 ]
Barua, Luna [1 ]
机构：
[1] VECC, BRIT, Reg Ctr, Radiopharmaceut Lab, Kolkata 700064, W Bengal, India
来源：
APPLIED RADIATION AND ISOTOPES | 2010年 / 68卷 / 01期
关键词：
(n; gamma)Mo-99; Tc-99m/Mo-99 solvent extraction generator; Methyl ethyl ketone; Purification; Alumina column chromatography; Na[Tc-99m]TcO4; LARGE ALUMINA COLUMN; MO-99; GENERATOR; MOLYBDATE; DOWEX-1; TANDEM;
D O I：
10.1016/j.apradiso.2009.07.024
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
A simple and inexpensive method of separation of Tc-99m from Mo-99 produced by neutron activation of Mo-99 via the Mo-99(n,gamma)Mo-99 nuclear reaction is described. The recovery of Tc-99m was performed by solvent extraction technique followed by column (active alumina) chromatography. The overall radiochemical yield for the complete separation of Tc-99m was 85-95% (n = 10). The separated Na[Tc-99m]TcO4 was of high radionuclidic, radiochemical, and chemical purities. The method can be adopted for routine use of Tc-99m in hospital radio-pharmacies utilizing low-medium specific activity (n,gamma)Mo-99 produced in a research reactor. (C) 2009 Elsevier Ltd. All rights reserved.
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页码：1 / 4
页数：4
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