Polycyclic aromatic compounds as anticancer agents: Synthesis and biological evaluation of dibenzofluorene derivatives

被引：66

作者：

Becker, FF ^{[1
]}

Mukhopadhyay, C ^{[1
]}

Hackfeld, L ^{[1
]}

Banik, I ^{[1
]}

Banik, BK ^{[1
]}

机构：

[1] Univ Texas, MD Anderson Canc Ctr, Dept Mol Pathol, Houston, TX 77030 USA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY | 2000年 / 8卷 / 12期

关键词：

D O I：

10.1016/S0968-0896(00)00213-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Highly regioselective electrophilic substitution of dibenzofluorene was achieved and the nitro derivative was transformed to a variety of new anticancer agents. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：2693 / 2699

页数：7

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