Effect of Plantago major on Burn Wound Healing in Rat

被引：56

作者：

Amini, M. ^{[2
]}

Kherad, M. ^{[2
]}

Mehrabani, D. ^{[1
]}

Azarpira, N. ^{[3
]}

Panjehshahin, M. R. ^{[4
]}

Tanideh, N. ^{[5
]}

机构：

[1] Shiraz Univ Med Sci, Nemazee Hosp, Dept Pathol, Gastroenterohepatol Res Ctr, Shiraz, Iran

[2] Shiraz Univ Med Sci, Sch Med, Dept Surg, Shiraz, Iran

[3] Shiraz Univ Med Sci, Transplant Res Ctr, Shiraz, Iran

[4] Shiraz Univ Med Sci, Sch Med, Dept Pharmacol, Shiraz, Iran

[5] Shiraz Univ Med Sci, Stem Cell & Transgen Biotechnol Res Ctr, Shiraz, Iran

来源：

JOURNAL OF APPLIED ANIMAL RESEARCH | 2010年 / 37卷 / 01期

关键词：

Silver sulfadiazine; Plantago major; wound; healing; epithelialization; rat; IN-VITRO; DRESSINGS; SILVER; CELL; NANOPARTICLES; CYTOTOXICITY;

D O I：

10.1080/09712119.2010.9707093

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

Amini, M., Kherad, M., Mehrabani, D., Azarpira, N., Panjehshahin, M.R. and Tanideh, N. 2010 Effect of Plantago major on burn wound healing in rat. J. Appl. Anim. Res., 37: 53-56. To determine the effect of Plantago major on healing of burn wounds, 100 male Sprague-Dawley 180-220 g rats were randomly divided into 4 groups. Groups of A, B and C each comprised of 30 rats, which were treated with silver sulfadiazine, 20% and 50% Plant ago major solution. Group D comprised of 10 rats, which were considered as control group and were treated with Oserin. After 7, 14 and 21 d of treatment, the animals were sacrificed, burn areas were examined histopathologically and scored. There was no significant difference between groups on d 7 and 14 but the difference was significant on d 21. The best results were noticed in group C receiving 50% P. major solution. So Plantago major may be a suitable substitute for silver sulfadiazine especially when applied in 50% concentration.

引用

页码：53 / 56

页数：4

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