Disease proteomics

被引：792

作者：

Hanash, S ^{[1
]}

机构：

[1] Univ Michigan, Dept Pediat, Ann Arbor, MI 48109 USA

来源：

NATURE | 2003年 / 422卷 / 6928期

关键词：

D O I：

10.1038/nature01514

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The sequencing of the human genome and that of numerous pathogens has opened the door for proteomics by providing a sequence-based framework for mining proteomes. As a result, there is intense interest in applying proteomics to foster a better understanding of disease processes, develop new biomarkers for diagnosis and early detection of disease, and accelerate drug development This interest creates numerous opportunities as well as challenges to meet the needs for high sensitivity and high throughput required for disease-related investigations.

引用

页码：226 / 232

页数：7

共 71 条

[1]

[Anonymous], 2002, Nature, V419, P323

[2]

Antelmann H, 2002, PROTEOMICS, V2, P591, DOI 10.1002/1615-9861(200205)2:5<591::AID-PROT591>3.0.CO

[3]

2-8

[4] Proteomic analysis of pharmacologically preconditioned cardiomyocytes reveals novel phosphorylation of myosin light chain 1 [J].