Lifestyle evolution in symbiotic bacteria: insights from genomics

被引:267
作者
Moran, NA [1 ]
Wernegreen, JJ
机构
[1] Univ Arizona, Dept Ecol & Evolutionary Biol, Tucson, AZ 85721 USA
[2] Univ Arizona, Ctr Insect Sci, Tucson, AZ 85721 USA
基金
美国国家科学基金会; 美国国家卫生研究院;
关键词
D O I
10.1016/S0169-5347(00)01902-9
中图分类号
Q14 [生态学(生物生态学)];
学科分类号
071012 ; 0713 ;
摘要
Bacteria that live only in eukaryotic cells and tissues, including chronic pathogens and mutualistic bacteriocyte associates, often possess a distinctive set of genomic traits, including reduced genome size, biased nucleotide base composition and fast polypeptide evolution. These phylogenetically diverse bacteria have lost certain functional categories of genes, including DNA repair genes, which affect mutational patterns. However, pathogens and mutualistic symbionts retain loci that underlie their unique interaction types, such as genes enabling nutrient provisioning by mutualistic bacteria-inhabiting animals, Recent genomic studies suggest that many of these bacteria are irreversibly specialized, precluding shifts between pathogenesis and mutualism.
引用
收藏
页码:321 / 326
页数:6
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