Histidine-Derived Nontoxic Nitrogen-Doped Carbon Dots for Sensing and Bioinnaging Applications

被引:145
作者
Huang, He [1 ]
Li, Chunguang [1 ]
Zhu, Shoujun [2 ]
Wang, Hailong [2 ]
Chen, Cailing [1 ]
Wang, Zhaorui [1 ]
Bai, Tianyu [1 ]
Shi, Zhan [1 ]
Feng, Shouhua [1 ]
机构
[1] Jilin Univ, Coll Chem, State Key Lab Inorgan Synth & Preparat Chem, Changchun 130012, Jilin, Peoples R China
[2] Jilin Univ, Coll Chem, State Key Lab Supramol Struct & Mat, Changchun 130012, Jilin, Peoples R China
基金
中国博士后科学基金;
关键词
POT GREEN SYNTHESIS; ONE-STEP SYNTHESIS; QUANTUM DOTS; NANODOTS; PHOTOLUMINESCENCE; NANOPARTICLES; GRAPHENE; PROBES; ROUTE;
D O I
10.1021/la503969z
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Nitrogen-doped (N-doped) photoluminescent carbon dots (CDs) were prepared by a one-pot microwaveassisted hydrothermal treatment using histidine as the sole carbon source in the absence of acid, alkali, or metal ions. With a diameter of 2 S nm, the synthesized CDs had apparent lattice fringes and exhibited an excitation-dependent photoluminescent behavior. The CDs were highly yielded, welldispersed in aqueous solution, and showed high photostability in the solutions of a wide range of pH and salinity. They were used as probes to identify the presence of Fel'. ions with a detection limit of 10 riM. With confirmed nontoxicit-y, these CDs could enter the cancer cells, indicating a practical potential for cellular imaging and labeling.
引用
收藏
页码:13542 / 13548
页数:7
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