Detecting oxidative post-translational modifications in proteins

被引:41
|
作者
Gianazza, E.
Crawford, J.
Miller, I.
机构
[1] Univ Milan, Dipartimento Sci Farmacol, Grp Studio Proteom & Struttura Prot, I-20133 Milan, Italy
[2] Nonlinear Dynam Ltd, Newcastle Upon Tyne, Tyne & Wear, England
[3] Vet Med Univ Wien, Inst Med Chem, Dept Nat Wissensch, Vienna, Austria
关键词
oxidative post-translational modifications; proteomics; electrophoresis; carbonylation; glutathionylation;
D O I
10.1007/s00726-006-0410-2
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Oxidative stress induces various post-translational modifications (PTM); some are reversible in vivo via enzymatic catalysis. The present paper reviews specific procedures for the detection of oxidative PTM in proteins, most of them including electrophoresis. Main topics are carbonylated and glutathionylated proteins as well as modification of selected amino acids ( Cys, Tyr, Met, Trp, Lys).
引用
收藏
页码:51 / 56
页数:6
相关论文
共 50 条
  • [1] Detecting oxidative post-translational modifications in proteins
    E. Gianazza
    J. Crawford
    I. Miller
    Amino Acids, 2007, 33 : 51 - 56
  • [2] Post-translational modifications of proteins
    Carr, SA
    FASEB JOURNAL, 1997, 11 (09): : A1121 - A1121
  • [3] Targeted mass spectrometry methods for detecting oxidative post-translational modifications
    Karina, Tveen-Jensen
    Ana, Reis
    Corinne, M. Spickett
    Andrew, R. Pitt
    FREE RADICAL BIOLOGY AND MEDICINE, 2014, 75 : S52 - S53
  • [4] Sirtuin Oxidative Post-translational Modifications
    Kalous, Kelsey S.
    Wynia-Smith, Sarah L.
    Smith, Brian C.
    FRONTIERS IN PHYSIOLOGY, 2021, 12
  • [5] Oxidative post-translational modifications in histones
    Luis Garcia-Gimenez, Jose
    Roma-Mateo, Carlos
    Pallardo, Federico V.
    BIOFACTORS, 2019, 45 (05) : 641 - 650
  • [6] Urinary Proteins with Post-translational Modifications
    Liu, Liu
    Liu, Xuejiao
    URINE PROTEOMICS IN KIDNEY DISEASE BIOMARKER DISCOVERY, 2015, 845 : 59 - 65
  • [7] Post-translational modifications of exosomal proteins
    Moreno-Gonzalo, Olga
    Villarroya-Beltri, Carolina
    Sanchez-Madrid, Francisco
    FRONTIERS IN IMMUNOLOGY, 2014, 5
  • [8] Post-translational modifications of the polycystin proteins
    Streets, Andrew
    Ong, Albert
    CELLULAR SIGNALLING, 2020, 72
  • [9] Post-translational modifications in prion proteins
    Otvos, L
    Cudic, M
    CURRENT PROTEIN & PEPTIDE SCIENCE, 2002, 3 (06) : 643 - 652
  • [10] POST-TRANSLATIONAL MODIFICATIONS OF POLIOVIRUS PROTEINS
    URZAINQUI, A
    CARRASCO, L
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1989, 158 (01) : 263 - 271