NTDB: Thermodynamic Database for Nucleic Acids, Version 2.0

被引：6

作者：

Chiu, WLAK ^{[1
]}

Sze, CN ^{[1
]}

Ma, NT ^{[1
]}

Chiu, LF ^{[1
]}

Leung, CW ^{[1
]}

Au-Yeung, SCF ^{[1
]}

机构：

[1] Chinese Univ Hong Kong, Dept Chem, Shatin, Hong Kong, Peoples R China

来源：

NUCLEIC ACIDS RESEARCH | 2003年 / 31卷 / 01期

关键词：

D O I：

10.1093/nar/gkg114

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The second release of Thermodynamic Database for Nucleic Acids, NTDB 2.0, includes more than 4600 entries ( 250% increase over release 1.0). It contains sequence types and details of several thermodynamic parameters ( enthalpy, DeltaH; entropy, DeltaH; Gibbs free energy, DeltaH; melting temperature, T-m), experimental models and methods for extracting thermodynamic parameters, buffer conditions as well as all relevant literature information. I addition, the database statistics and references related to NTDB are included. Information on normal and modified nucleobases and nucleosides are collected in a new section Nucleoside whereby data collected thus far will be release in NTDB 2.0. The NTDB is freely available at http: / / ntdb. chem. cuhk. edu. hk.

引用

页码：483 / 485

页数：3

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