Brief screening tool for mild cognitive impairment in older Japanese: Validation of the Japanese version of the Montreal Cognitive Assessment

被引：415

作者：

Fujiwara, Yoshinori ^{[1
]}

Suzuki, Hiroyuki

Yasunaga, Masashi

Sugiyama, Mika ^{[2
]}

Ijuin, Mutsuo ^{[2
]}

Sakuma, Naoko ^{[2
]}

Inagaki, Hiroki ^{[2
]}

Iwasa, Hajime ^{[4
]}

Ura, Chiaki ^{[2
]}

Yatomi, Naomi ^{[2
]}

Ishii, Kenji ^{[3
]}

Tokumaru, Aya M. ^{[5
]}

Homma, Akira ^{[6
]}

Nasreddine, Ziad ^{[7
]}

Shinkai, Shoji

机构：

[1] Tokyo Metropolitan Inst Gerontol, Res Team Social Participat & Community Hlth, Itabashi Ku, Tokyo 1730015, Japan

[2] Tokyo Metropolitan Inst Gerontol, Res Team Promoting Independence Elderly, Tokyo 1730015, Japan

[3] Tokyo Metropolitan Inst Gerontol, Positron Med Ctr, Tokyo 1730015, Japan

[4] Univ Tokyo, Grad Sch Med, Tokyo 1138654, Japan

[5] Tokyo Metropolitan Med Ctr Gerontol, Dept Diagnost Radiol, Tokyo, Japan

[6] Ctr Dementia Care Res & Training Tokyo, Tokyo, Japan

[7] Univ Sherbrooke, Clin Res Ctr, Neurol Serv, Hop Charles LeMoyne, Sherbrooke, PQ J1K 2R1, Canada

来源：

GERIATRICS & GERONTOLOGY INTERNATIONAL | 2010年 / 10卷 / 03期

关键词：

elderly; mild cognitive impairment; screening; Japanese version of the Montreal Cognitive Assessment; MINI-MENTAL-STATE; DEMENTIA; MORTALITY; DISEASE; HEALTH; MOCA;

D O I：

10.1111/j.1447-0594.2010.00585.x

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Aim: The Montreal Cognitive Assessment (MoCA), developed by Dr Nasreddine (Nasreddine et al. 2005), is a brief cognitive screening tool for detecting older people with mild cognitive impairment (MCI). We examined the reliability and validity of the Japanese version of the MoCA (MoCA-J) in older Japanese subjects. Methods: Subjects were recruited from the outpatient memory clinic of Tokyo Metropolitan Geriatric Hospital or community-based medical health check-ups in 2008. The MoCA-J, the Mini-Mental State Examination (MMSE), the revised version of Hasegawa's Dementia Scale (HDS-R), Clinical Dementia Rating (CDR) scale, and routine neuropsychological batteries were conducted on 96 older subjects. Mild Alzheimer's disease (AD) was found in 30 subjects and MCI in 30, with 36 normal controls. Results: The Cronbach's alpha of MoCA-J as an index of internal consistency was 0.74. The test-retest reliability of MoCA, using intraclass correlation coefficient between the scores at baseline survey and follow-up survey 8 weeks later was 0.88 (P < 0.001). MoCA-J score was highly correlated with MMSE (r = 0.83, P < 0.001), HDS-R (r = 0.79, P < 0.001) and CDR (r = -0.79, P < 0.001) scores. The areas under receiver-operator curves (AUC) for predicting MCI and AD groups by the MoCA-J were 0.95 (95% confidence interval [CI] = 0.90-1.00) and 0.99 (95% CI = 0.00-1.00), respectively. The corresponding values for MMSE and HDS-R were 0.85 (95% CI = 0.75-0.95) and 0.97 (95% CI = 0.00-1.00), and 0.86 (95% CI = 0.76-0.95) and 0.97 (95% CI = 0.00-1.00), respectively. Using a cut-off point of 25/26, the MoCA-J demonstrated a sensitivity of 93.0% and a specificity of 87.0% in screening MCI. Conclusion: The MoCA-J could be a useful cognitive test for screening MCI, and could be recommended in a primary clinical setting and for geriatric health screening in the community. Geriatr Gerontol Int 2010; 10: 225-232.

引用

页码：225 / 232

页数：8

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