Aza-Peterson Olefinations: Rapid Synthesis of (E)-Alkenes

被引：5

作者：

Britten, Thomas K. ^{[1
]}

Basson, Ashley J. ^{[1
]}

Roberts, Dean D. ^{[1
]}

McLaughlin, Mark G. ^{[1
]}

机构：

[1] Manchester Metropolitan Univ, Dept Nat Sci, Chester St, Manchester M1 5GD, Lancs, England

来源：

SYNTHESIS-STUTTGART | 2021年 / 53卷 / 19期

基金：

英国医学研究理事会;

关键词：

Peterson olefination; imines; allylsilanes; Schlosser's base; 1,3-dienes; stilbenes; ACID-PROMOTED ADDITION; CARBONYL-COMPOUNDS; CARBANIONS-ALPHA; ROUTE; EFFICIENT; REAGENTS; ALKENES; 1,3-BIS(SILYL)PROPENES; METALATION; SUPERBASES;

D O I：

10.1055/a-1493-6670

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An aza-Peterson olefination methodology to access 1,3dienes and stilbene derivatives from the corresponding allyl- or benzyltrimethylsilane is described. Silanes can be deprotonated using Schlosser's base and added to N-phenyl imines or ketones to directly give the desired products in high yields.

引用

页码：3535 / 3544

页数：10

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