Health-related quality of life and antihypertensive medication adherence among older adults

被引：75

作者：

Holt, Elizabeth Winter ^{[1
]}

Muntner, Paul ^{[2
]}

Joyce, Cara Jean ^{[3
]}

Webber, Larry ^{[3
]}

Krousel-Wood, Marie A. ^{[1
,4
]}

机构：

[1] Alton Ochsner Med Fdn & Ochsner Clin, Ctr Hlth Res, New Orleans, LA 70121 USA

[2] Univ Alabama Birmingham, Dept Epidemiol, Birmingham, AL USA

[3] Tulane Univ, Sch Publ Hlth & Trop Med, Dept Biostat, New Orleans, LA USA

[4] Tulane Univ, Sch Publ Hlth & Trop Med, Dept Epidemiol, New Orleans, LA USA

来源：

AGE AND AGEING | 2010年 / 39卷 / 04期

关键词：

HRQOL; medication adherence; hypertension; older adults; elderly; DEPRESSIVE SYMPTOMS; CLINICAL-OUTCOMES; BLOOD-PRESSURE; HYPERTENSION; NONCOMPLIANCE;

D O I：

10.1093/ageing/afq040

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Methods: participants were part of a cohort study of older adults enrolled in a managed care organisation and treated for hypertension (n = 2,180). Physical and Mental Component Summary Scores (PCS and MCS) of HRQOL were assessed using the RAND Medical Outcomes Study 36-item tool. Adherence to antihypertensive medication was assessed with the eight-item Morisky Medication Adherence Scale. Results: the mean age of participants was 75.0 +/- 5.6 years, 69.3% were white, 58.5% were women and 14.1% had low antihypertensive medication adherence. Low HRQOL scores were associated with lower levels of antihypertensive medication adherence in older adults. After adjustment for covariates, those with low PCS and MCS scores were 1.33 (95% CI 1.01, 1.74) and 2.26 (95% CI 1.74, 2.97) times more likely, respectively, to have low antihypertensive medication adherence than those with PCS and MCS scores in the top 2 tertiles. Conclusions: low HRQOL may be an important barrier to achieving high medication adherence.

引用

页码：481 / 487

页数：7

共 29 条

[1] A NEW METHOD OF CLASSIFYING PROGNOSTIC CO-MORBIDITY IN LONGITUDINAL-STUDIES - DEVELOPMENT AND VALIDATION [J].

CHARLSON, ME ;

POMPEI, P ;

ALES, KL ;

MACKENZIE, CR .

JOURNAL OF CHRONIC DISEASES, 1987, 40 (05) :373-383

[2] Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure [J].

Chobanian, AV ;

Bakris, GL ;

Black, HR ;

Cushman, WC ;

Green, LA ;

Izzo, JL ;

Jones, DW ;

Materson, BJ ;

Oparil, S ;

Wright, JT ;

Roccella, EJ .

HYPERTENSION, 2003, 42 (06) :1206-1252

[3] Is adherence to drug treatment correlated with health-related quality of life? [J].

Côté, I ;

Farris, K ;

Feeny, D .

QUALITY OF LIFE RESEARCH, 2003, 12 (06) :621-633

[4] Health-related quality of life in patients treated for hypertension: A review of the literature from 1990 to 2000 [J].

Coyne, KS ;

Davis, D ;

Frech, F ;

Hill, MN .

CLINICAL THERAPEUTICS, 2002, 24 (01) :142-169

[5] Depression is a risk factor for noncompliance with medical treatment -: Meta-analysis of the effects of anxiety and depression on patient adherence [J].

DiMatteo, MR ;

Lepper, HS ;

Croghan, TW .

ARCHIVES OF INTERNAL MEDICINE, 2000, 160 (14) :2101-2107

[6] FACTORS ASSOCIATED TO PATIENTS' NONCOMPLIANCE WITH HYPERTENSION TREATMENT [J].

Dosse, Camila ;

Cesarino, Claudia Bernardi ;

Vilela Martin, Jose Fernando ;

Andrade Castedo, Maria Carolina .

REVISTA LATINO-AMERICANA DE ENFERMAGEM, 2009, 17 (02) :201-206

[7]

Gandek B, 2004, HEALTH CARE FINANC R, V25, P5

[8] Compliance and hypertension [J].

Garfield F.B. ;

Caro J.J. .

Current Hypertension Reports, 1999, 1 (6) :502-506

[9] MEASURING HEALTH-RELATED QUALITY-OF-LIFE [J].

GUYATT, GH ;

FEENY, DH ;

PATRICK, DL .

ANNALS OF INTERNAL MEDICINE, 1993, 118 (08) :622-629

[10] Helping patients follow prescribed treatment - Clinical applications [J].

Haynes, RB ;

McDonald, HP ;

Garg, AX .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2002, 288 (22) :2880-2883

← 1 2 3 →