Gold-Catalyzed Benzannulation of 3-Alkoxy-1,5-enynes: Access to Functionalized Benzenes

被引：17
|
作者：
Li, Guijie [1 ]
Liu, Yuanhong [1 ]
机构：
[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2010年 / 75卷 / 09期
基金：
中国国家自然科学基金;
关键词：
HIGHLY EFFICIENT SYNTHESIS; AROMATIC ENYNES; CYCLIZATION; CYCLOISOMERIZATION; PLATINUM; HYDROXYCYCLIZATION; ALKOXYCYCLIZATION; ALKYNES; HETEROCYCLES; CARBOCYCLES;
D O I：
10.1021/jo100137j
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A cationic Au(I) complex catalyzed benzannulation of 3-alkoxy-1,5-enynes bridged by a cyclopropyl ring with a variety of nucleophiles is described. The reaction occurs selectively through a 6-endo-dig pathway to provide tri- and tetrasubstituted benzenes efficiently under mild reaction conditions.
引用
收藏
页码：2903 / 2909
页数：7
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