Colorectal Cancer Screening in Inflammatory Bowel Disease

被引：21

作者：

Sengupta, Neil ^{[1
]}

Yee, Eric ^{[2
]}

Feuerstein, Joseph D. ^{[1
]}

机构：

[1] Beth Israel Deaconess Med Ctr, Div Gastroenterol, 110 Francis St 8E Gastroenterol, Boston, MA 02215 USA

[2] Beth Israel Deaconess Med Ctr, Div Pathol, Boston, MA 02215 USA

来源：

DIGESTIVE DISEASES AND SCIENCES | 2016年 / 61卷 / 04期

关键词：

Colon cancer screening; Inflammatory bowel disease; Ulcerative colitis; Crohn's disease; PRIMARY SCLEROSING CHOLANGITIS; CHRONIC ULCERATIVE-COLITIS; POPULATION-BASED COHORT; EVIDENCE-BASED CONSENSUS; LOW-GRADE DYSPLASIA; COLONOSCOPIC SURVEILLANCE; INCREASED RISK; ADEQUATE TREATMENT; IMPROVES SURVIVAL; CROHNS-DISEASE;

D O I：

10.1007/s10620-015-3979-z

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Patients with long-standing ulcerative colitis (UC) or Crohn's colitis are at increased risk of developing colorectal cancer (CRC). Given that most cases of CRC are thought to arise from dysplasia, previous guidelines have recommended endoscopic surveillance with random biopsies obtained from all segments of the colon involved by endoscopic or microscopic inflammation. However, recent evidence has suggested that the majority of dysplastic lesions in patients with inflammatory disease (IBD) are visible, and data have been supportive of chromoendoscopy with targeted biopsies of visible lesions versus traditional random biopsies. This review article will discuss the risk of colon cancer in patients with IBD, as well as current recommendations for CRC screening and surveillance in patients with UC or Crohn's colitis.

引用

页码：980 / 989

页数：10

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