Colorectal Cancer Screening in Inflammatory Bowel Disease

被引:21
作者
Sengupta, Neil [1 ]
Yee, Eric [2 ]
Feuerstein, Joseph D. [1 ]
机构
[1] Beth Israel Deaconess Med Ctr, Div Gastroenterol, 110 Francis St 8E Gastroenterol, Boston, MA 02215 USA
[2] Beth Israel Deaconess Med Ctr, Div Pathol, Boston, MA 02215 USA
关键词
Colon cancer screening; Inflammatory bowel disease; Ulcerative colitis; Crohn's disease; PRIMARY SCLEROSING CHOLANGITIS; CHRONIC ULCERATIVE-COLITIS; POPULATION-BASED COHORT; EVIDENCE-BASED CONSENSUS; LOW-GRADE DYSPLASIA; COLONOSCOPIC SURVEILLANCE; INCREASED RISK; ADEQUATE TREATMENT; IMPROVES SURVIVAL; CROHNS-DISEASE;
D O I
10.1007/s10620-015-3979-z
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Patients with long-standing ulcerative colitis (UC) or Crohn's colitis are at increased risk of developing colorectal cancer (CRC). Given that most cases of CRC are thought to arise from dysplasia, previous guidelines have recommended endoscopic surveillance with random biopsies obtained from all segments of the colon involved by endoscopic or microscopic inflammation. However, recent evidence has suggested that the majority of dysplastic lesions in patients with inflammatory disease (IBD) are visible, and data have been supportive of chromoendoscopy with targeted biopsies of visible lesions versus traditional random biopsies. This review article will discuss the risk of colon cancer in patients with IBD, as well as current recommendations for CRC screening and surveillance in patients with UC or Crohn's colitis.
引用
收藏
页码:980 / 989
页数:10
相关论文
共 89 条
[1]   Colonoscopy Is Associated With a Reduced Risk for Colon Cancer and Mortality in Patients With Inflammatory Bowel Diseases [J].
Ananthakrishnan, Ashwin N. ;
Cagan, Andrew ;
Cai, Tianxi ;
Gainer, Vivian S. ;
Shaw, Stanley Y. ;
Churchill, Susanne ;
Karlson, Elizabeth W. ;
Murphy, Shawn N. ;
Kohane, Isaac ;
Liao, Katherine P. .
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2015, 13 (02) :322-U163
[2]   European evidence based consensus for endoscopy in inflammatory bowel disease [J].
Annese, Vito ;
Daperno, Marco ;
Rutter, Matthew D. ;
Amiot, Aurelien ;
Bossuyt, Peter ;
East, James ;
Ferrante, Marc ;
Goetz, Martin ;
Katsanos, Konstantinos H. ;
Kiesslich, Ralf ;
Ordas, Ingrid ;
Repici, Alessandro ;
Rosa, Bruno ;
Sebastian, Shaji ;
Kucharzik, Torsten ;
Eliakim, Rami .
JOURNAL OF CROHNS & COLITIS, 2013, 7 (12) :982-1018
[3]  
[Anonymous], 2003, GASTROINTEST ENDOSC, V58, pS3
[4]   Chemoprevention of colorectal neoplasia: The potential for personalized medicine [J].
Arber, Nadir ;
Levin, Bernard .
GASTROENTEROLOGY, 2008, 134 (04) :1224-1237
[5]   Family history as a risk factor for colorectal cancer in inflammatory bowel disease [J].
Askling, J ;
Dickman, PW ;
Karlén, P ;
Broström, O ;
Lapidus, A ;
Löfberg, R ;
Ekbom, A .
GASTROENTEROLOGY, 2001, 120 (06) :1356-1362
[6]   Age at diagnosis of inflammatory bowel disease influences early development of colorectal cancer in inflammatory bowel disease patients: a nationwide, long-term survey [J].
Baars, J. E. ;
Kuipers, E. J. ;
van Haastert, M. ;
Nicolai, J. J. ;
Poen, A. C. ;
van der Woude, C. J. .
JOURNAL OF GASTROENTEROLOGY, 2012, 47 (12) :1308-1322
[7]   The Risk of Inflammatory Bowel Disease-Related Colorectal Carcinoma Is Limited: Results From a Nationwide Nested Case-Control Study [J].
Baars, Judith E. ;
Looman, Caspar W. N. ;
Steyerberg, Ewout W. ;
Beukers, Ruud ;
Tan, Adriaan C. I. T. L. ;
Weusten, Bas L. A. M. ;
Kuipers, Ernst J. ;
van der Woude, Christien J. .
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2011, 106 (02) :319-328
[8]   Cancers Complicating Inflammatory Bowel Disease [J].
Beaugerie, Laurent ;
Itzkowitz, Steven H. .
NEW ENGLAND JOURNAL OF MEDICINE, 2015, 372 (15) :1441-1452
[9]   Risk of Colorectal High-Grade Dysplasia and Cancer in a Prospective Observational Cohort of Patients With Inflammatory Bowel Disease [J].
Beaugerie, Laurent ;
Svrcek, Magali ;
Seksik, Philippe ;
Bouvier, Anne-Marie ;
Simon, Tabassome ;
Allez, Matthieu ;
Brixi, Hedia ;
Gornet, Jean-Marc ;
Altwegg, Romain ;
Beau, Philippe ;
Duclos, Bernard ;
Bourreille, Arnaud ;
Faivre, Jean ;
Peyrin-Biroulet, Laurent ;
Flejou, Jean-Francois ;
Carrat, Fabrice .
GASTROENTEROLOGY, 2013, 145 (01) :166-+
[10]  
BLACKSTONE MO, 1981, GASTROENTEROLOGY, V80, P366