Infection of bovine oviduct cell cultures with Chlamydophila abortus

被引：4

作者：

Appino, Simonetta

Pregel, Paola

Manuali, Elisabetta

Vincenti, Leila

Rota, Ada

Carnieletto, Paola

Tiberi, Cinzia

Bollo, Enrico

机构：

[1] Univ Sassari, Ist Patol Gen Anat Patol & Clin Ostetr Chirurg Ve, I-07100 Sassari, Italy

[2] Univ Turin, Dipartimento Patol Anim, I-10095 Turin, Italy

[3] Ist Zooprofilatt Sperimentale Umbria & Marche, I-06126 Perugia, Italy

[4] Ist Zooprofilatt Sperimentale Venezie, I-35020 Legnaro, Padova, Italy

来源：

ANIMAL REPRODUCTION SCIENCE | 2007年 / 98卷 / 3-4期

关键词：

bovine infertility; cell culture; Chlamydophila abortus; oviduct; in vitro model;

D O I：

10.1016/j.anireprosci.2006.03.006

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

Bovine infertility is a major cause of loss in the livestock industry. In the present study bovine oviduct cell cultures were infected with a Chlamydophila abortus strain. A direct evaluation of infection was performed by means of May Grunwald-Giemsa and immunocytochemistry for chlamydial LPS, which revealed inclusion bodies and vacuolisation. SEM and TEM analysis of infected cells showed various degrees of cell damage and conglutination of microvilli. This finding suggests that cattle infertility may result from an alteration of oviduct environment caused by multiplication of C. abortus. This microorganism, among other infectious agents, could be considered a potential causative agent of bovine infertility. (c) 2006 Elsevier B.V. All rights reserved.

引用

页码：350 / 356

页数：7

共 18 条

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