Anorexia Nervosa and Premenopausal Osteoporosis A Case Report

The premenopausal osteoporosis observed in patients with anorexia nervosa (AN) has traditionally been attributed to depressed ovarian estrogen synthesis. For many years, estrogen replacement was the accepted standard of care. Newer research, however, reveals the multifactorial nature of bone deterioration in the presence of undernutrition and supports a more comprehensive approach to treatment. This case of a young woman with AN-induced osteoporosis highlights the need for interprofessional collaboration among physicians, dietitians, and mental health professionals. It underscores the challenges associated with medical and nutritional management of skeletal decline in the context of an eating disorder.