New bioactive polyacetylenes from the marine sponge Petrosia sp.

被引：41
作者：
Kim, JS
Im, KS
Jung, JH [1 ]
Kim, YL
Kim, J
Shim, CJ
Lee, CO
机构：
[1] Pusan Natl Univ, Coll Pharm, Pusan 609735, South Korea
[2] Seoul Natl Univ, Coll Pharm, Seoul 151742, South Korea
[3] Han Nam Univ, Dept Biol, Taejon, South Korea
[4] KRICT, Pharmaceut Screening Ctr, Taejon, South Korea
来源：
TETRAHEDRON | 1998年 / 54卷 / 13期
关键词：
D O I：
10.1016/S0040-4020(98)00066-0
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Four new polyacetylenes (3-6) with cytotoxic activities against human tumor cell lines (A549, SK-OV-3, SK-MEL-2, XF498, and HCT15) have been isolated from the marine sponge Petrosia sp. They were given the trivial names of dideoxypetrosynols A-D. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
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页码：3151 / 3158
页数：8
相关论文
共 20 条
[1]  
Bohlmann F, 1973, NATURALLY OCCURRING
[2]   MINOR BIOACTIVE POLYACETYLENES FROM PETROSIA-FICIFORMIS [J].
CIMINO, G ;
DEGIULIO, A ;
DEROSA, S ;
DIMARZO, V .
JOURNAL OF NATURAL PRODUCTS, 1990, 53 (02) :345-353
[3]   MARINE NATURAL-PRODUCTS [J].
FAULKNER, DJ .
NATURAL PRODUCT REPORTS, 1995, 12 (03) :223-269
[4]   BIOACTIVE MARINE METABOLITES .20. PETROSYNOL AND PETROSYNONE, ANTIMICROBIAL C30 POLYACETYLENES FROM THE MARINE SPONGE PETROSIA SP - DETERMINATION OF THE ABSOLUTE-CONFIGURATION [J].
FUSETANI, N ;
SHIRAGAKI, T ;
MATSUNAGA, S ;
HASHIMOTO, K .
TETRAHEDRON LETTERS, 1987, 28 (37) :4313-4314
[5]   ANTIFUNGAL BROMINATED C-18 ACETYLENIC ACIDS FROM THE MARINE SPONGE, PETROSIA-VOLCANO HOSHINO [J].
FUSETANI, N ;
LI, HY ;
TAMURA, K ;
MATSUNAGA, S .
TETRAHEDRON, 1993, 49 (06) :1203-1210
[6]   BIOACTIVE MARINE METABOLITES .3. A NOVEL POLYACETYLENE ALCOHOL, INHIBITOR OF CELL-DIVISION IN FERTILIZED SEA-URCHIN EGGS, FROM THE MARINE SPONGE TETROSIA SP [J].
FUSETANI, N ;
KATO, Y ;
MATSUNAGA, S ;
HASHIMOTO, K .
TETRAHEDRON LETTERS, 1983, 24 (27) :2771-2774
[7]   NEW ACETYLENIC ALCOHOLS FROM THE SPONGE CRIBROCHALINA-VASCULUM [J].
GUNASEKERA, SP ;
FAIRCLOTH, GT .
JOURNAL OF ORGANIC CHEMISTRY, 1990, 55 (25) :6223-6225
[8]   ABSOLUTE STEREOCHEMISTRY OF PETROFORMYNES, HIGH-MOLECULAR POLYACETYLENES FROM THE MARINE SPONGE PETROSIA-FICIFORMIS [J].
GUO, YW ;
GAVAGNIN, M ;
TRIVELLONE, E ;
CIMINO, G .
TETRAHEDRON, 1994, 50 (46) :13261-13268
[9]   FURTHER STRUCTURAL STUDIES ON THE PETROFORMYNES [J].
GUO, YW ;
GAVAGNIN, M ;
TRIVELLONE, E ;
CIMINO, G .
JOURNAL OF NATURAL PRODUCTS-LLOYDIA, 1995, 58 (05) :712-722
[10]   Antitumor activity and stereochemistry of acetylenic alcohols from the sponge Cribrochalina vasculum [J].
Hallock, YF ;
Cardellina, JH ;
Blaschak, MS ;
Alexander, MR ;
Prather, TR ;
Shoemaker, RH ;
Boyd, MR .
JOURNAL OF NATURAL PRODUCTS, 1995, 58 (12) :1801-1807
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