New bioactive polyacetylenes from the marine sponge Petrosia sp.

被引:41
|
作者
Kim, JS
Im, KS
Jung, JH [1 ]
Kim, YL
Kim, J
Shim, CJ
Lee, CO
机构
[1] Pusan Natl Univ, Coll Pharm, Pusan 609735, South Korea
[2] Seoul Natl Univ, Coll Pharm, Seoul 151742, South Korea
[3] Han Nam Univ, Dept Biol, Taejon, South Korea
[4] KRICT, Pharmaceut Screening Ctr, Taejon, South Korea
关键词
D O I
10.1016/S0040-4020(98)00066-0
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Four new polyacetylenes (3-6) with cytotoxic activities against human tumor cell lines (A549, SK-OV-3, SK-MEL-2, XF498, and HCT15) have been isolated from the marine sponge Petrosia sp. They were given the trivial names of dideoxypetrosynols A-D. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:3151 / 3158
页数:8
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